Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Prof Gareth Veal
+44 (0)191 208 4332
g.j.veal@newcastle.ac.uk


Study Location:

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Be Part of Research - Trial Details - Therapeutic drug monitoring in children with cancer

Therapeutic drug monitoring in children with cancer

Medical Conditions

Cancer


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 May 2019 30 Nov 2028

Publications

2024 Results article in https://pubmed.ncbi.nlm.nih.gov/39549227/ (added 19/11/2024)

Observational

Intervention Type : Other
Intervention Description : The trial will recruit an estimated 150 patients within defined 'hard to treat' categories. These include pre-term infants and newborns, patients with impaired kidney function or no kidneys, patients receiving high dose chemotherapy, obese patients, and those receiving chemotherapy where the drug is injected directly into the tumour.Patients will be referred to the study following decisions made by their treating clinician to use Therapeutic Drug Monitoring as part of the patient's standard treatment.Clinical and response data will be collected following each cycle of treatment and all relevant clinical information and data generated will be entered into a patient registry in an anonymised form available only to registered medical staff with individual password-protected user accounts. Clinicians will then be able to use this information when treating future patients within these 'hard to treat' groups.




You can take part if:



You may not be able to take part if:


Failure to meet the inclusion criteria.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • John Radcliffe Hospital
    Headley Way Headington
    Oxford
    OX3 9DU
  • Royal Victoria Infirmary
    Queen Victoria Road
    Newcastle upon Tyne
    NE1 4LP
  • Southampton General Hospital
    Tremona Road
    Southampton
    SO16 6YD
  • Great Ormond Street Hospital
    Great Ormond Street
    London
    WC1N 3JH
  • Sheffield Children's Hospital
    Western Bank
    Sheffield
    S10 2TH
  • Birmingham Children’s Hospital
    Steelhouse Lane
    Birmingham
    B4 6NH
  • Royal Aberdeen Children’s Hospital
    Westburn Road
    Aberdeen
    AB25 2ZG
  • University College Hospital London
    250 Euston Road
    London
    NW1 2PG
  • Royal Manchester Children’s Hospital
    Oxford Road
    Manchester
    M13 9WL
  • Alder Hey Children’s Hospital
    Eaton Road
    Liverpool
    L12 2AP
  • Bristol Royal Hospital for Children
    Upper Maudlin Street
    Bristol
    BS2 8BJ
  • Addenbrooke’s Hospital
    Hills Road
    Cambridge
    CB2 2QQ
  • Children’s Hospital of Wales
    Heath Park
    Cardiff
    CF14 4XW
  • Royal Hospital for Sick Children, Edinburgh
    Sciennes Road
    Edinburgh
    EH9 1LF
  • Royal Hospital for Sick Children, Glasgow
    1345 Govan Road
    Glasgow
    G51 4TF
  • Leeds General Infirmary,
    Great George St
    Leeds
    LS1 3EX
  • Queens Medical Centre
    Derby Rd
    Nottingham
    NG7 2UH

This information has not yet been provided by the study team. You'll have an opportunity to discuss any risks and benefits that may be associated with this study prior to consenting to taking part.


The study is sponsored by Newcastle upon Tyne Hospitals NHS Foundation Trust and funded by National Institute for Health Research.




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Read full details for Trial ID: ISRCTN10139334
Last updated 19 November 2024

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