Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Mr Binoy Kumaran
+44 (0)7517430077
b.r.kumaran@herts.ac.uk


Mr Tim Watson
+44 (0)1707 284000
t.watson@herts.ac.uk


Study Location:

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Be Part of Research - Trial Details - Clinical effects of radiofrequency based therapy

Clinical effects of radiofrequency based therapy

Not Recruiting

Open to: All Genders

Age: Adult

Medical Conditions

Osteoarthritis (OA) of the knee joint


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Osteoarthritis (OA), the most common type of arthritis, is a condition that causes joints to become painful and stiff. OA typically affects the knees, hips and small joints of the hands. OA is an incurable, long term condition but there are a number of ways to improve symptoms, such as maintaining a healthy weight and regularly exercising. Unfortunately, OA of the knee can often result in disability and make it hard for people to carry out their normal daily activities. It can also make it difficult for people to exercise. Physiotherapists can help people put together an exercise plan to manage their symptoms. They can also provide various treatments to reduce pain and swelling in the joints, such as radiofrequency (RF) therapy. RF therapy generates heat in the tissues of the affected area, which increases blood flow and relieves pain and inflammation. The standard RF therapy given to patients is shortwave therapy, which delivers a 27.12 Megahertz frequency to the affected joint. There are various types of devices available, including ones that operate at very low frequencies (below 1 Megahertz), although it is not clear how well they actually work. Capacitive Resistive Monopolar Radiofrequency (CRMRF) (448 Kilohertz) is one such low frequency device. The aim of this study is to see how well CRMRF therapy works to relieve pain and improve quality of life in patients suffering from chronic OA of the knee compared to standard therapy. CRMRF will be delivered using the Indiba Activ 902 device.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

15 Jun 2015 30 Jun 2016

Publications

2019 Results article in https://pubmed.ncbi.nlm.nih.gov/30269963/ results (added 02/09/2020)

Participants are randomly allocated into one of three groups. Those in group 1 (intervention group) receive CRMRF therapy alongside standard RF therapy. Those in group 2 (placebo group) receive ‘dummy’ CRMRF therapy alongside standard RF therapy. Those in group 3 (control group) receive standard care only. All participants receive treatment twice a week for four weeks. Participants are assessed for pain and quality of life using questionnaires before, immediately after, and one and three months following treatment. Participants take part in the study for a total of four months.


Adults diagnosed with OA of the knee.

You can take part if:



You may not be able to take part if:


1. Significant underlying medical conditions2. OA of other joints such as hip or ankle3. Currently receiving/received (in the last six months) treatment (including invasive procedures) other than standard care4. Inability to consent


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Hertfordshire Community NHS Trust
    Welwyn Garden City
    AL7 1BW

The results will help identify whether adding CRMRF to the current care provides any 'added value', and also whether it provides better results than an equivalent placebo treatment. The study will also provide useful data for further research.


The study is sponsored by University of Hertfordshire and funded by INDIBA SA (Spain).





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Read full details for Trial ID: ISRCTN10995065
Last updated 02 September 2020

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