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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Miss Chara Triantafyllou
+44 (0) 117 414 8182
chara.triantafyllou@bristol.ac.uk


Study Location:

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Be Part of Research - Trial Details - Can mindfulness and lifestyle interventions improve the memory and mental function in people who are starting to notice a decline in their memory and thinking abilities?

Can mindfulness and lifestyle interventions improve the memory and mental function in people who are starting to notice a decline in their memory and thinking abilities?

Not Recruiting

Open to: All Genders

Age: Adult

Medical Conditions

Subjective cognitive decline (SCD)


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


At present there is little to offer to people who are concerned about their memory and thinking abilities, in terms of support or treatment. This is because these people do not have serious problems with daily living and do not have any formal diagnosis. Even if they visit a specialist, they will usually be discharged without any further recommendations. However, this lack of support might leave them feeling confused and anxious. The aim of this study is to develop a new online course and test it against already available courses to examine whether these would be effective interventions for people who are worried about their memory. We also aim to describe the characteristics of these people and assess how these characteristics might be related to the risk of future memory problems.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

24 Jan 2017 01 Sep 2017

We are asking participants to attend three visits at Southmead Hospital, in Bristol (baseline, 6 weeks later and 6 months later). During these visits the examiners will give them some pen-and-paper tests to assess their memory and thinking abilities and their quality of life. The participants will be divided into three groups. Two of the groups involve an online course where participants are asked to watch some video presentations for 4 weeks. One of the courses aims to inform them about relaxation and stress relief techniques (mindfulness meditation) while the other one is about lifestyle factors that could make our brains healthier (like diet and exercise). The third is a control group where participants will just wait until the next visit. We are also asking participants to give an optional blood sample, but this is not a requirement for entering the study. The blood sample will help us see if some people are at higher risk of memory lapses.


Adults over the age of 45 who are concerned about their memory.

You can take part if:



You may not be able to take part if:


1. Has a current diagnosis or history of any type of cognitive impairment or dementia, or has a current diagnosis of neurological/psychiatric disorder or any other diagnosis that significantly affects cognitive performance (including substance abuse)2. Incapable of doing a brisk walk3. Has been exposed to the cognitive tests performed in this study within 6 months prior to the baseline assessment4. Score on MoCA test is <20. An individual with a MoCA score this low may have significant cognitive decline (Larner, 2012) and should be referred to their GP. 5. Knows his or her own ApoE genotype/phenotype6. Cannot adequately understand verbal explanations or written information given in English


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Southmead Hospital
    North Bristol NHS Trust Southmead Road Westbury-on-Trym
    Bristol
    BS10 5NB

Through this study, participants will have the chance to participate in an educational course that could possibly improve their quality of life. Regarding the risks, there is a potential for upset, because of the questionnaire’s sensitive nature. In the unlikely event that someone feels uncomfortable with the tests, they can discuss this with the examiner and/or withdraw at any point without giving any reason. The study also involves an optional blood sample. The physical risks of giving this blood sample are the same as any blood sample taken from a vein. Participants may experience minor bruising or irritation.


The study is sponsored by University of Bristol and funded by BRACE.




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Read full details for Trial ID: ISRCTN16149416
Last updated 21 February 2019

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.