Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Prof David Taggart
-
david.taggart@orh.nhs.uk


Study Location:

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Be Part of Research - Trial Details - Coronary artery grafting in high risk patients randomised to off-pump or on-pump surgery

Coronary artery grafting in high risk patients randomised to off-pump or on-pump surgery

Stopped

Open to: All Genders

Age: Adult

Medical Conditions

Coronary heart disease


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Not provided at time of registration

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Jan 2009 24 Mar 2011

Publications

2014 Results article in http://www.ncbi.nlm.nih.gov/pubmed/25023641 results

Interventional

Intervention Type : Procedure/Surgery
Intervention Description : This study is an international, multicentre open randomised controlled trial, across 40 centres: 20 in the UK and 20 overseas. Trial patients will be randomised to:1. CABG without cardiopulmonary bypass, i.e. off-pump CABG (OPCABG) on the beating heart, via a median sternotomy incision2. CABG with cardiopulmonary bypass i.e. on-pump CABG (ONCABG) on a chemically arrested heart, via a median sternotomy incision

Total duration of follow-up is 1 year post-surgery.




You can take part if:



You may not be able to take part if:


Current information as of 05/03/2010:1. Euroscore <5 2. Emergency operation (immediate revascularisation for haemodynamic instability) 3. Concomitant cardiac procedure with CABG 4. Operation to be carried out via an incision other than a median sternotomy (e.g. anterolateral left thoracotomy) 5. Known contraindication to ONCABG or OPCABG (e.g. calcified aorta, calcified coronaries, small target vessels)

Initial information at time of registration:1. Male patient under 70 years of age with good left ventricular function (ejection fraction greater than 50%)2. Euroscore less than 5 3. Emergency operation (immediate revascularisation for haemodynamic instability)4. Concomitant cardiac procedure with CABG 5. Operation to be carried out via an incision other than a median sternotomy (e.g. anterolateral left thoracotomy)6. Contraindication to ONCABG or OPCABG (e.g. calcified aorta, intramuscular left anterior descending [LAD], calcified coronaries, small target vessels)


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • John Radcliffe Hospital
    Oxford
    OX3 9DU

This information has not yet been provided by the study team. You'll have an opportunity to discuss any risks and benefits that may be associated with this study prior to consenting to taking part.

Prof David Taggart
-
david.taggart@orh.nhs.uk



The study is sponsored by University of Oxford (UK) and funded by Medical Research Council (MRC) (UK) (ref: G0700469).




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Read full details for Trial ID: ISRCTN29161170

Or CPMS 4333

Last updated 12 June 2015

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