Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr Sarah Goldberg
+44 (0)115 8230543
sarah.goldberg@nottingham.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - Promoting Activity, Independence and Stability in Early Dementia and Mild Cognitive Impairment 2

Promoting Activity, Independence and Stability in Early Dementia and Mild Cognitive Impairment 2

Not Recruiting

Open to: All Genders

Age: Senior

Medical Conditions

Dementia, mild cognitive impairment


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


People with memory problems can struggle with everyday activities and may stop doing things they want to do. They are more prone to accidents and have a higher risk of falling. Occupational therapists can advise how to do daily activities more easily and safely. Physiotherapists can teach exercises which increase activity and improve balance, and may help maintain memory. There is little research on how to make these interventions work for with people with memory problems. The aim of this study is to compare an activity and exercise programme developed for people with memory problems to standard falls prevention assessment and advice.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

10 Sep 2018 23 Jun 2021

Publications

2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31888709 protocol (added 02/01/2020)2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32859666/ protocol (added 02/09/2020)2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/35858870/ results of the sub-set of the PrAISED study participants receiving the intervention during during a lockdown in response to the COVID-19 pandemic (added 21/07/2022)2022 Preprint results in https://doi.org/10.1101/2022.12.20.22283699 Primary and secondary results (added 03/01/2023)2023 Preprint results in https://doi.org/10.1101/2023.03.26.23287750 Commissioner and stakeholder perspectives (added 31/03/2023)2023 Results article in https://doi.org/10.1136/bmj-2023-074787 (added 30/08/2023)2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37603841/ (added 06/12/2023)2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38650466/ (added 24/04/2024)

Participants are randomly allocated to either the control group or the intervention group. The control group receive standard brief falls assessment and advice, and up to two further visits if required. The intervention group receive an assessment, tailored strength and balance exercise programme, activity analysis and risk enablement advice, and assessment for environmental hazards. The intervention is delivered over 1 year in participants’ own homes, and is tailored to individual interests, abilities and need for supervision. Participants are encouraged to exercise by themselves or with family members between visits, and once the programme ends. Researchers visit at the start of the study and after 12 months to measure ability in activities of daily living, activity, quality of life, memory and health service use. Participants complete monthly falls diaries over 15 months. The researchers conduct interviews and video record some therapy sessions to help understand how the programme works in practice.


Patients aged 65 or over with early dementia or memory problems, recruited from memory clinics or the ‘Join Dementia Research’ register

You can take part if:



You may not be able to take part if:


1. Co-morbidity preventing participation (e.g. severe breathlessness, pain, psychosis, Parkinson’s or other severe neurological disease)2. Life expectancy of less than one year3. Likely to be unable to undertake the intervention regularly (e.g. planned elective surgery, planning to move away or commitments elsewhere).


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Nottinghamshire Healthcare NHS Foundation Trust
    Nottingham
    NG3 6AA
  • Lincolnshire Partnership NHS Foundation Trust
    Lincoln
    NG34 8GG
  • Derbyshire Healthcare NHS Foundation Trust
    Centre for Research and Development Kingsway Hospital
    Derby
    DE22 3LZ
  • RICE - Research Institute for the Care of Older People
    The RICE Centre Royal United Hospital Combe Park
    Bath
    BA1 3NG
  • CRN East Midlands
    Knighton Street Outpatients 1st Floor, Leicester Royal Infirmary
    Leicester
    LE1 5WW
  • Oxford Health NHS Foundation Trust
    Research and Development Department Warneford Hospital Warneford Lane
    Oxford
    OX3 7JX

Some participants may benefit from taking part in the intervention, as exercise is generally known to be beneficial to health and well-being, including benefits to heart, blood pressure, diabetes, joints, mood and daily life. These participants may find that they are better able to do their daily activities. All participants and their relatives may enjoy having the researchers coming to visit them in their house. Some people appreciate having the opportunity to contribute to the well-being of others through research.

Dr Sarah Goldberg
+44 (0)115 8230543
sarah.goldberg@nottingham.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by Nottingham University Hospitals NHS Trust and funded by NIHR Central Commissioning Facility (CCF); Grant Codes: RP-PG-0614-20007.




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Read full details for Trial ID: ISRCTN15320670

Or CPMS 36405

Last updated 24 April 2024

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