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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Neal Navani
n.navani@ucl.ac.uk


Sindhu Naidu
s.naidu@ucl.ac.uk


Sindhu Naidu
s.naidu@ucl.ac.uk


Study Location:

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Be Part of Research - Trial Details - Observational study of lung cancer in never-smokers

Observational study of lung cancer in never-smokers

Recruiting

Open to: Female / Male

Age: 18 Years - 100 Years

Medical Conditions

Malignant neoplasms of respiratory and intrathoracic organs


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study aims to understand lung cancer in never-smokers (LCINS) and improve the early detection and
management of these patients.

Lung cancer is one of the most common cancers in the United Kingdom (UK). Although it is typically associated with smoking,more than a quarter of adults diagnosed with lung cancer have never smoked. Such individuals may have different risk factors,symptoms and so on. However,compared to people who have smoked,there are no specific ways to improve the diagnosis of lung cancer in never-smokers. Understanding more about LCINS may help contribute to earlier diagnosis and reduce the number of people dying from this disease.

The people who take part in this study will not have any changes made to their usual clinical care. Instead,most of the data will come from their primary and secondary care electronic health records. Data that will be collected includes what symptoms people had before their diagnosis,possible risk factors such as other medical problems,and what happens to them after they get diagnosed. Other things which may be related to LCINS,such as pollution data,may also be measured.

People who have never smoked and who have been diagnosed or treated with lung cancer at hospitals which are part of the study will be invited to join this study. Although people are not expected to directly benefit as a result of participating in this study,they may benefit from knowing they will contribute to research that may help to improve the understanding and diagnosis of lung cancer in never-smokers like them.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Sep 2024 01 Apr 2029

Observational

Observational type: Cohort study;



You can take part if:



You may not be able to take part if:


• Participants who have ever smoked cigarettes or tobacco will be excluded; this is defined as - More than 100 cigarettes or 75g tobacco in their lifetime . - Those who have received a prescription for nicotine replacement therapy. • For prospective participants, those who cannot consent will be excluded.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

Sindhu Naidu
s.naidu@ucl.ac.uk


Sindhu Naidu
s.naidu@ucl.ac.uk


Neal Navani
n.navani@ucl.ac.uk



The study is sponsored by UNIVERSITY COLLEGE LONDON HOSPITALS NHS FOUNDATION TRUST and funded by NIHR Academy .




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for Trial ID: CPMS 74857

Last updated 23 July 2026

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