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Contact Information:

Reference Study ID Number: GA45977 https://forpatients.roche.com/ 888-662-6728 (U.S.)
global-roche-genentech-trials@gene.com


Study Location:

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Be Part of Research - Trial Details - A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Ulcerative Colitis


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to evaluate the efficacy of RO7837195 compared with placebo in participants with moderately to severely active ulcerative colitis for whom prior treatment with conventional and/or advanced therapies has failed.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Sep 2025 Aug 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : RO7837195 will be administered as per the schedule specified in the protocol.

Intervention Arm Group : RO7837195 Dose Regimen 1;RO7837195 Dose Regimen 2;RO7837195 Dose Regimen 3;RO7837195 Dose Regimen 4;RO7837195 Matched Placebo/ RO7837195;

Intervention Type : DRUG
Intervention Description : RO7837195 matched placebo will be administered as per the schedule specified in the protocol.

Intervention Arm Group : RO7837195 Matched Placebo/ RO7837195;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • John Radcliffe Hospital
    Oxford
    Oxfordshire
    OX3 9DU
  • Guy's Hospital
    London
    Greater London
    SE1 9RT
  • King's College Hospital
    London
    Greater London
    SE5 9RS
  • Royal Liverpool University Hospital
    Liverpool
    Merseyside
    L7 8YE
  • Addenbrook'es Hospital
    Cambridge
    CB2 0QQ

Reference Study ID Number: GA45977 https://forpatients.roche.com/ 888-662-6728 (U.S.)
global-roche-genentech-trials@gene.com



The study is sponsored by Genentech, Inc.




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Read full details for Trial ID: NCT06979336
Last updated 01 May 2026

This page is to help you find out about a research study and if you may be able to take part

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