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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Fausto
Biancari
fausto.biancari@hus.fi
Prof
Tatu
Juvonen
tatu.juvonen@hus.fi
Type A aortic dissection
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as an emergency or salvage procedure and is associated with increased postoperative early mortality and morbidity. Although early mortality has declined over the last years, it remains significant in Western countries. The Nordic Consortium for Acute Type A Aortic Dissection registry, including 1189 patients operated on from 2005 to 2015 in 8 centers showed that 30-day mortality after surgery for acute TAAD was 18%. The multicenter, prospective German Registry for Acute Aortic Dissection Type A, including 2137 TAAD patients operated from 2006 and 2010, documented a 30-day mortality of 16.9%. A more recent analysis of the Society of Thoracic Surgeons database, including 7353 patients operated on from 2014 and 2017 for acute TAAD, reported a 30-day mortality of 17%. Furthermore, surgery for TAAD is often complicated by major adverse events such as stroke and acute kidney failure, which may have a significant impact on late survival. In this scenario of significant postoperative mortality and morbidity, surgeons face the controversial issue of the extent of surgical repair for acute TAAD by avoiding a major surgical repair with its possible increased risk of early adverse events. However, limited aortic repair may expose the patient to the risk of late complications at the level of the aortic root, the aortic arch and/or the downstream aorta. We planned the multicenter Transatlantic Registry of Type A Aortic Dissection (TARTAAD) for a thorough evaluation of the early and late outcomes of acute TAAD after different surgical and perfusion strategies in patients operated at several European and North American cardiac surgery centers.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
You can take part if:
You may not be able to take part if:
1. Patients aged < 18 years2. Onset of symptoms > 7 days from surgery3. Prior procedure for TAAD4. Type non-A non-B aortic dissection5. Retrograde TAAD (with primary tear located in descending aorta)6 Concomitant endocarditis7. TAAD secondary to blunt or penetrating chest trauma
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by Helsinki University Hospital and funded by Helsingin ja Uudenmaan Sairaanhoitopiiri.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
