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Be Part of Research - Trial Details - A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Recruiting

Open to: ALL

Age: 18.0 - 80.0

Medical Conditions

Radiographic Axial Spondyloarthritis


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Researchers are looking for new ways to treat radiographic axial spondyloarthritis (r-axSpA). R-axSpA is a type of arthritis that causes pain, stiffness, and inflammation (swelling) in the spine and joints in the pelvis (hip bone). Radiographic means the damage it causes can be seen on X-rays.

This study will help find out if a study medicine called tulisokibart can treat symptoms of r-axSpA. Researchers will look at different doses of tulisokibart.

Researchers want to know if at least one of the study doses of tulisokibart works better than a placebo to improve r-axSpA symptoms. A placebo looks like the study medicine but has no study medicine in it. Using a placebo helps researchers better understand the effects of the study medicine.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Sep 2025 Jun 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Subcutaneous (SC) administration

Intervention Arm Group : High-dose tulisokibart;Low-dose tulisokibart;Medium-dose tulisokibart;

Intervention Type : DRUG
Intervention Description : SC administration

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Norfolk & Norwich University Hospital NHS Foundation Trust ( Site 1800)
    Norwich
    Norfolk
    NR4 7UY
  • Barnet Hospital ( Site 1806)
    Barnet
    EN5 3DJ
  • Royal United Hospital Bath NHS Foundation Trust ( Site 1803)
    Bath
    Somerset
    BA1 3NG


The study is sponsored by Merck Sharp & Dohme LLC





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Read full details for Trial ID: NCT07133633
Last updated 25 March 2026

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.