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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr Upasana Tayal
preg-heart@imperial.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

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Be Part of Research - Trial Details - A UK-wide, direct-to-patient platform for studying cardiovascular disease in pregnancy
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A UK-wide, direct-to-patient platform for studying cardiovascular disease in pregnancy

Recruiting

Open to: Female

Age: Mixed

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Medical Conditions

Cardiovascular disease in pregnancy

This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study aims to improve our understanding of the impact of cardiovascular (heart) disease on pregnancy, on the long-term effects of pregnancy on women with cardiovascular disease, and on how best to treat and manage cardiovascular disease during pregnancy and the postnatal period.
Up to 4% of pregnant women have cardiovascular disease, and cardiovascular disease in pregnancy is a leading cause of harm for mothers and babies. However, because there are many different types of cardiovascular disease which can affect pregnant women, and these women live in different parts of the country and receive care in different hospitals, it is difficult for studies to recruit enough women with specific cardiovascular conditions for research. This makes it hard for researchers to build an understanding of how these diseases behave in pregnancy and to develop better treatments.
The purpose of this study is therefore to create an online research platform where women with cardiovascular disease in pregnancy, alongside women without cardiovascular disease (to act as a healthy control group), can self-identify, provide consent to share information about their health and pregnancies, and agree to participate in research. This will help to remove some of the barriers to participation in research for this patient group (for example, barriers associated with living in particular parts of the country, receiving care in certain hospitals, or not having the means to travel to participate in research visits).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

25 Nov 2025 31 Jan 2028

Participants will be invited to register on an online platform (PREG-HEART), provide consent electronically, and enter information about themselves, their health, and their current and/or previous pregnancies.
Information about the health of participants, and the outcome of their pregnancies, will be collected using questionnaires which they will be invited to complete when they register on the platform, after the end of their pregnancy, and up to once a year following this.
Participants will also be able to give their consent to provide samples (for example of blood, urine, or saliva) for future research use. They may also give consent to be contacted in order to be invited to participate in additional studies about cardiovascular health in pregnancy.


Women aged 16 years or older are eligible to take part in the study if:
1. They are currently or have previously been pregnant, and have cardiovascular disease which was diagnosed prior to, during, or in the 6 months after pregnancy (cases); OR
2. They are currently pregnant, with no diagnosis of cardiovascular disease (healthy controls)

You can take part if:



You may not be able to take part if:


1. Patients who lack capacity to consent for themselves2. People who do not have access to the Internet and/or who are unable to provide an email address for study correspondence


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

There will be no direct benefits from taking part in this study, but the results may help to improve the healthcare of pregnant women in the future. As this is an observational study, the risk of adverse effects due to participation are unlikely to occur.

Dr Upasana Tayal
preg-heart@imperial.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by Imperial College London and funded by National Institute for Health and Care Research; British Heart Foundation.



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Read full details for Trial ID: ISRCTN11700499
Last updated 26 November 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.   

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