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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Royal Free Hospital, London
- Professor Rezan Abdul-Kadir / Natasha Ford
020 3758 2000, extension 33863
rf-tr.rhandcresearch@nhs.net
Royal Cornwall Hospital, Truro
- Dr Karen Watkins
01872 228856
Rcht.cioscrdc@nhs.net
St Mary’s Hospital, Imperial
- Dr Edward Mullins / Jena Strawford / Farhana Mehar
020 3312 6948
imperial.paediatricresearch@nhs.net
Princess Royal Hospital, Telford
- Professor William Parry-Smith
01952 565939
Sath.research.maty@nhs.net
Southampton General Hospital
- Professor Chrissie Jones / Nicki Martin
023 8220 6856
Reprohealthresearcht@uhs.nhs.uk
St Mary’s Hospital, Manchester
- Dr Teresa Kelly / Debbie Pillar / Anj Chambers
0161 701 3480
Beatrix@mft.nhs.uk
St James’s University Hospital, Leeds
- Dr Nigel Simpson
0113 206 6473
leedsth-tr.beatrixstudy@nhs.net
St Michael’s Hospital, Bristol
- Dr Sneha Basude
0117 342 5756
research_st.michaels@uhbw.nhs.uk
St George’s Hospital, London
- Professor Asma Khalil / Gauri Kumar
020 8725 5382
BeatrixStudy@sgul.ac.uk
John Radcliffe Hospital, Oxford
- Dr Manu Vatish / Kate Bailey / Jude Mossop
01865 221107
clinicalresearchgroup@wrh.ox.ac.uk
Group B Strep Infection Group B Streptococcus Group B Streptococcus Infection
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
BEATRIX (group B strEptococcus mATeRnal and Infant VaX study) The purpose of this study is to learn about the safety and how the group B streptococcus (GBS) vaccine works in pregnant women and their babies.
This study is seeking healthy pregnant participants:
* aged 49 or younger who can join.
* between 24 and 36 weeks of gestation ("Gestational age" is a medical term used to describe how far along your pregnancy is)
* had a fetal ultrasound examination performed with no major fetal abnormalities observed
* documented negative for HIV, syphilis and Hepatitis B All participants in this study will receive only 1 shot in an arm. This could either be a group B streptococcus 6-valent polysaccharide conjugate vaccine (GBS6) or placebo. Placebo is an inactive substance used in the study for comparison purposes; in this study, the placebo injection will be saline (saltwater). The pregnant participants may take part in this study for a maximum of 14 months (6 months after delivery) , and their babies for about 12 months after they are born. The pregnant participants will need to visit the research site at least 3 to 4 times with some visits permitted to occur over the telephone.
A subset of infants will be asked to take part in the study for up to 19 months. The subset will receive diphtheria toxoid-containing vaccine and/or pneumococcal vaccine following each country's standard immunization plan and have blood drawn 1 month after completion of the primary and/or toddler (booster) doses.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
You can take part if:
You may not be able to take part if:
This is in the inclusion criteria above
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Princess Royal Hospital, Telford
- Professor William Parry-Smith
01952 565939
Sath.research.maty@nhs.net
John Radcliffe Hospital, Oxford
- Dr Manu Vatish / Kate Bailey / Jude Mossop
01865 221107
clinicalresearchgroup@wrh.ox.ac.uk
St Michael’s Hospital, Bristol
- Dr Sneha Basude
0117 342 5756
research_st.michaels@uhbw.nhs.uk
Southampton General Hospital
- Professor Chrissie Jones / Nicki Martin
023 8220 6856
Reprohealthresearcht@uhs.nhs.uk
Royal Free Hospital, London
- Professor Rezan Abdul-Kadir / Natasha Ford
020 3758 2000, extension 33863
rf-tr.rhandcresearch@nhs.net
St Mary’s Hospital, Manchester
- Dr Teresa Kelly / Debbie Pillar / Anj Chambers
0161 701 3480
Beatrix@mft.nhs.uk
Royal Cornwall Hospital, Truro
- Dr Karen Watkins
01872 228856
Rcht.cioscrdc@nhs.net
St Mary’s Hospital, Imperial
- Dr Edward Mullins / Jena Strawford / Farhana Mehar
020 3312 6948
imperial.paediatricresearch@nhs.net
St George’s Hospital, London
- Professor Asma Khalil / Gauri Kumar
020 8725 5382
BeatrixStudy@sgul.ac.uk
St James’s University Hospital, Leeds
- Dr Nigel Simpson
0113 206 6473
leedsth-tr.beatrixstudy@nhs.net
The study is sponsored by Pfizer
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
