Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Prof Neil French
N.French@liverpool.ac.uk


Mrs Rampy Kumar
Lymeuk@liverpool.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - LYME-UK – A study of early Lyme disease within GPs in the UK

LYME-UK – A study of early Lyme disease within GPs in the UK

Recruiting

Open to: All Genders

Age: Mixed

Medical Conditions

Lyme disease


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Lyme disease is a bacterial infection that occurs in humans through the bite of an infected tick. This is known as a vector-borne disease and Lyme disease is the most common vector-borne disease in the United Kingdom, Europe, and North America. Despite increasing public concern and media attention, there is limited knowledge about how many infections occur, how we accurately diagnose these, and what the long-term outcomes of infections are within the UK. The overall aim is to understand the disease and treatment outcomes over a year, in patients who attend their GP with suspected Lyme disease and are treated with antibiotics.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

26 Jul 2023 31 Mar 2029

The study requires 3 clinical visits, to collect blood and urine sample at 3 timepoints, and an optional skin biopsy at baseline. We will also ask symptoms questionnaires over 12 months at 10 timepoints.


Adults aged 18 and over.

You can take part if:



You may not be able to take part if:


1. Contraindication to blood sampling2. Extreme frailty and/or comorbidity with poor life expectancy3. Long term antibiotic use


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • NHS Highland
    Reay House 17 Old Edinburgh Road
    Inverness
    IV2 3HG

This study will provide data from the tick bite, symptoms, treatment outcomes and serology profile for patients with a diagnosed early infection, within the UK. Participating in the study will enable participants to contribute towards baseline and follow-up data, to help improve understanding of diagnosis and treatment outcomes in patients. Clinical samples will be used in future research to understand Lyme disease infection and to develop improved and new ways to diagnose Lyme disease earlier and more accurately. There is no direct benefit for participants – travel will be reimbursed up to £20 per visit. There is some risk associated with providing a blood sample, with potential discomfort and a small risk of bruising. For participants that provide consent for a skin punch biopsy, there is an additional small risk of infection and discomfort from the procedure. You may also be asked to attend for an extra clinic visit to check healing and removal of a suture if this is used in the procedure.

Prof Neil French
N.French@liverpool.ac.uk


Mrs Rampy Kumar
Lymeuk@liverpool.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by University of Liverpool and funded by NIHR Central Commissioning Facility (CCF); Grant Codes: NIHR200907.




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Read full details for Trial ID: ISRCTN16352397

Or CPMS 60167

Last updated 17 February 2026

This page is to help you find out about a research study and if you may be able to take part

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