Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Prof Jane Murphy
jane.murphy@dorsetgp.nhs.uk


Prof Mary Hickson
mary.hickson@plymouth.ac.uk


Dr . Refresh PenCTU
refresh.penctu@plymouth.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - REFRESH study: nutRition intervEntions For malnouRished oldEr adultS in care Homes - A parallel, superiority, three-arm cluster randomised controlled trial

REFRESH study: nutRition intervEntions For malnouRished oldEr adultS in care Homes - A parallel, superiority, three-arm cluster randomised controlled trial

Medical Conditions

Malnutrition


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Many older people living in care homes are at risk of malnutrition, which means they aren’t getting the nutrients they need. This can lead to poor health, lower quality of life, and a higher chance of falls and infections. The REFRESH study will compare three approaches to nutritional care: fortified foods, supplement drinks, and usual care. Around 1,530 residents from 90 care homes will take part to help find out which approach works best to improve nutrition and quality of life.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Nov 2025 31 May 2027

Once eligible care home residents (or consultees) have agreed to take part in the study, initial information will be collected (baseline data). Each care home will then be randomly placed into one of three groups. Residents will receive one of the following for 12 months:
• Oral nutritional supplements: Two ready-to-drink supplements each day between meals, alongside their usual diet.
• Fortified food: Meals, snacks and drinks made with extra protein, calories, vitamins and minerals, alongside their usual diet.
• Usual care: The care home will continue with their usual approach to nutrition for residents who are malnourished.
Further information will be collected at 6 months and again at 12 months.


Participants will be older adults (65 years or over) with or at risk of malnutrition, living in a care home which has applied to take part and met certain care home inclusion criteria.

You can take part if:



You may not be able to take part if:


Current key exclusion criteria as of 12/06/2026:

1. Fed via feeding tube2. Active cancer treatment or recent major surgery3. Considered by the care home staff to be approaching the end of life, where participation in the study would not be appropriate.4. Already receiving nutrition support (ONS or fortified meals) with individualised dietetic advice from a dietitian‡.

‡Residents will be eligible if they have been:a. prescribed ONS short term (e.g. after a hospital stay) and have not yet been reviewed by a dietitian.b. prescribed ONS not specifically for malnutrition (e.g. for wound healing, haemo-dialysis).c. prescribed ONS by or on the recommendation of a health professional other than a dietitian (e.g. nurse or GP).d. discharged from dietetic care but are still on ONS.

_____

Previous key exclusion criteria as of 12/06/2026:

1. Fed via feeding tube2. Already receiving nutrition support (ONS or fortified meals) on the advice of a healthcare professional (e.g. GP) and/or individualised dietetic advice3. Active cancer treatment or recent major surgery4. Considered by the care home staff to be approaching the end of life, where participation in the study would not be appropriate‡. ‡In cases where there is uncertainty, this decision will be made collaboratively by care home staff, in consultation with the resident (where possible), and a consultee (if applicable). Care home staff, who are leading initial discussions about the study, will use their professional judgment on a case-by-case basis to ensure that the decision reflects the resident’s condition, preferences, and advice of the consultee (if applicable).


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Primley Court Nursing Home
    13 Primley Park
    Paignton
    TQ3 3JW
  • Camelot House and Lodge
    Taunton Rd
    Wellington
    TA21 9HY
  • Mount Olivet Nursing Home
    2 Great Headland Road
    Paignton
    TQ3 2DY
  • Upton Bay Care Home
    1 Hoyal Road
    Poole
    BH15 4HY
  • Oakhill Mansions
    College Park Drive Westbury-on-trym
    Bristol
    BS10 7QD
  • Hill House Nursing Home
    Park Avenue
    Brixham
    TQ5 0DT
  • Sheridan House
    10c Douglas Avenue
    Exmouth
    EX8 2BT
  • West Eaton House
    Worcester Road
    Leominster
    HR6 0QJ
  • Summerdyne Nursing Home
    Cleobury Road Wyre Hill
    Bewdley
    DY12 2QQ
  • The Lawns Nursing Home
    33 Main Road Kempsey
    Worcester
    WR5 3NF
  • Atholl House Nursing Home
    98-100 Richmond Road Compton
    Wolverhampton
    WV3 9JJ
  • Trafalgar Care Home
    207 Dorchester Road
    Weymouth
    DT4 7LF
  • Waltham House
    Stoke Park Road, Stoke Bishop
    Bristol
    BS9 1JF
  • Three Corners
    3 Greenway Road Galmpton
    Brixham
    TQ5 0LW
  • Pendruccombe House
    23 Tavistock Road
    Launceston
    PL15 9HF
  • Valley Court
    Valley Road
    Cradley Heath
    B64 7LT
  • Elmwood
    Swan Hill Road Colyford
    Colyton
    EX24 6QJ
  • Parkwood House
    72-74 Exmouth Road Stoke
    Plymouth
    PL1 4QJ
  • Hillcrest House
    Barbican Road
    Looe
    PL13 1NN
  • Larkhall Springs Nursing Home
    Swainswick Gardens Larkhall
    Bath
    BA1 6TL
  • Hurstway
    142 the Hurstway
    Birmingham
    B23 5XN
  • Cole Valley Nursing Home
    326 Haunch Lane Kings Heath
    Birmingham
    B13 0PN
  • Asher Care
    120 Ashburton Road
    Newton Abbot
    TQ12 1RJ
  • Arbour Walk
    7-21 Hungerford Road
    Bristol
    BS4 5HU
  • Davlyn House
    41 Bull Lane Brindley Ford
    Stoke-on-trent
    ST8 7QL
  • Neville Williams House
    8-14 Greenland Road Selly Park
    Birmingham
    B29 7PP
  • Resthaven CIO
    15 Gussiford Lane
    Exmouth
    EX8 2SD
  • Woodlands Quaker Home
    434 Penn Road Penn
    Wolverhampton
    WV4 4DH
  • Anglebury Court
    21 Bonnets Lane,
    Wareham
    BH22 4HB
  • Seaview Haven
    Oaktree Gardens Highfield Road
    Ilfracombe
    EX34 9JP
  • Fordingbridge Care Home
    Station Road
    Fordingbridge
    SP6 1JW

We cannot guarantee there will be any benefits from taking part in the study as we do not know what the results will be. However, the participants’ involvement will contribute to the development of new knowledge and understanding of malnutrition in care homes, which could help to improve the care of older people in the future.
There is a chance that the oral nutritional supplements or the fortified food may cause the following:
- Gastrointestinal symptoms (i.e., constipation, bloating, nausea)
- Poorly controlled blood glucose (blood sugar levels that are too high or too low) in those with diabetes.
These effects may occur whichever group the participant is in, including usual care if these options are used as part of it. If necessary, the food or supplement which is thought to be the cause would be stopped.

Prof Mary Hickson
mary.hickson@plymouth.ac.uk


Prof Jane Murphy
jane.murphy@dorsetgp.nhs.uk


Dr . Refresh PenCTU
refresh.penctu@plymouth.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by University of Plymouth and funded by National Institute for Health and Care Research.




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Read full details for Trial ID: ISRCTN15687909

Or CPMS: 58561

Last updated 12 June 2026

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