Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Amgen Call Center 866-572-6436
medinfo@amgen.com


Study Location:

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Be Part of Research - Trial Details - Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Medical Conditions

Atherosclerotic Cardiovascular Disease
Overweight
Obesity


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The primary objective of this trial is to demonstrate that maridebart cafraglutide is superior to placebo when given as an adjunct to standard of care with respect to reducing cardiovascular (CV) morbidity and mortality.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jul 2025 Jun 2028

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Maridebart cafraglutide will be administered SC.

Intervention Arm Group : Maridebart Cafraglutide;

Intervention Type : DRUG
Intervention Description : Placebo will be administered SC.

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Queen Mary University of London
    London
    EC1M 6BQ
  • Glenfield Hospital
    Leicester
    LE3 9QP
  • Addenbrookes Hospital
    Cambridge
    CB2 0QQ
  • Lister Hospital
    Stevenage
    SG1 4AB
  • University Hospital Coventry
    Coventry
    CV2 2DX
  • Worcestershire Royal Hospital
    Worcester
    WR5 1DD
  • Southmead Hospital
    Bristol
    BS10 5NB
  • Musgrove Park Hospital
    Taunton
    TA1 5DA
  • Royal Devon and Exeter Hospital
    Exeter
    EX2 5DW
  • Hull Royal Infirmary
    Hull
    HU3 2JZ
  • University Hospital Llandough
    Penarth
    CF64 2XX
  • Ninewells Hospital and Medical School
    Dundee
    DD1 9SY
  • Glasgow Royal Infirmary
    Glasgow
    G31 2ER
  • Countess of Chester Hospital
    Chester
    CH2 1UL
  • Heartlands Hospital
    Birmingham
    B9 5SS
  • Torbay Hospital
    Torquay
    TQ2 7AA
  • St Georges Hospital
    London
    SW17 0QT
  • West Walk Surgery
    Bristol
    BS37 4AX
  • Bradford on Avon and Melksham Health Partnership
    Wiltshire
    BA15 1DQ
  • Staploe Medical Centre
    Ely
    CB7 5JD
  • Waterloo Medical Centre
    Blackpool
    FY4 3AD
  • Wycombe Hospital
    High Wycombe
    HP11 2TT
  • Morriston Hospital
    Swansea
    SA2 8PP
  • Northenden Group Practice
    Manchester
    M22 4DH
  • Russell Hall Hospital
    Dudley
    DY1 2HQ
  • Salford Royal Hospital
    Salford
    M5 5AP
  • Newcastle NIHR Commercial Research Delivery Centre
    Newcastle upon Tyne
    NE1 4LP
  • Chelsea and Westminster Hospital
    London
    SW10 9NH

Amgen Call Center 866-572-6436
medinfo@amgen.com



The study is sponsored by Amgen




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Read full details for Trial ID: NCT07037433
Last updated 13 May 2026

This page is to help you find out about a research study and if you may be able to take part

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