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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Diabetic foot ulcer
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
The main focus of this research concerns diabetic foot ulcers. The raised blood sugar levels of those with diabetes can cause nerve damage and loss of sensation in the feet. This allows ‘painless’ wounds to go unnoticed and get worse over time. Raised blood sugar levels can also lead to the narrowing of vessels and reduced blood flow to the feet. Loss of foot sensation and reduced blood flow can leave a person with diabetes vulnerable to developing patches of broken skin under the foot that are difficult to heal, known as diabetic foot ulcers. Doctors advise people with diabetic foot ulcers to stay off their feet as much as possible to help heal an ulcer. This often leads to high amounts of sitting time and reduced time spent being physically active which can further worsen their health over time. Keeping diabetic foot ulcer patients physically active while remaining off their feet is an area of research that is yet to be explored. The aim of this study is to investigate whether 12 weeks of seated upper-body exercise training using an arm ergometer (for a minimum of 30 minutes, three times per week) can improve fitness, health, quality of life, physical function, body composition and ulcer area in this population.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32565482/ protocol (added 16/02/2021)
You can take part if:
Current inclusion criteria as of 03/05/2023:
1. Actively receiving or has received DFU treatment within the previous 12 months
2. Aged > = 18 years of age
3. Able to undertake upper body arm exercise (specifically arm ergometry)
4. Deemed safe to exercise further to cardiac nurse evaluation at baseline
5. Participant is willing to give informed consent to take part
You may not be able to take part if:
1. Uncontrolled hyperglycaemia (HbA1c > 10% - Confirmed through baseline blood sample results)2. Report taking part in regular (at least once a week) strenuous sport or activities3. Under weight or with a Body Mass Index of < = 18.5 kg/m24. Existing heart problem (a cardiovascular event within the last 12 months or screened by cardiac nurse at baseline)5. Co-morbidity that the research team consider to be a contraindication to their study involvement6. Unable to communicate in written or verbal English7. Unable to provide written informed consent
* In the circumstance that an individual is not sure whether they meet the necessary criteria, they will be reviewed by a medic (named on the delegation log) for a clinical decision to be made during their baseline visit (prior to engaging in any study-related tasks)
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Matthew
McCarthy
+44 (0)116 258 4323
mm636@le.ac.uk
The study is sponsored by University of Leicester and funded by Diabetes UK; Grant Codes: 18/0005883,; Novo Nordisk UK Research Foundation; Grant Codes: RM65G0161.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
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You can print or share the study information with your GP/healthcare provider or contact the research team directly.
