Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Reference Study ID Number: WN45447 https://forpatients.roche.com/ 888-662-6728
global-roche-genentech-trials@gene.com


Study Location:

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Be Part of Research - Trial Details - A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Recruiting

Open to: ALL

Age: 50.0 - 90.0

Medical Conditions

Alzheimers Disease


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Nov 2025 Jun 2028

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Participants will receive IV trontinemab

Intervention Arm Group : Trontinemab;

Intervention Type : OTHER
Intervention Description : Participants will receive IV placebo

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Southampton University Hospitals NHS Trust
    Southampton
    SO16 6YD
  • Warneford Hospital
    Oxford
    OX3 7JX
  • St George?s Hospital
    London
    SW17 ORE
  • UCL Institute of Neurology
    London
    WC1N 3BG
  • Queen Elizabeth University Hospital Glasgow
    Glasgow
    G51 4TF
  • Re:Cognition Health Birmingham
    Birmingham
    B16 8QQ
  • Scottish Brain Sciences
    Edinburgh
    EH12 9DQ
  • RE:Cognition Health
    London
    W1G 8TA
  • Manchester Mental Health and Social Care Trust
    Manchester
    M13 9WL
  • ReMind UK
    Bath
    BA1 3NG
  • Lancashire and South Cumbria NHS Foundation Trust
    Preston
    PR2 8DW

Reference Study ID Number: WN45447 https://forpatients.roche.com/ 888-662-6728
global-roche-genentech-trials@gene.com



The study is sponsored by Hoffmann-La Roche




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Read full details for Trial ID: NCT07170150
Last updated 12 March 2026

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.