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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Gurvinder Gill
gurvinder.gill@nihr.ac.uk


Laurna Bullock
l.bullock@keele.ac.uk


Baksho Kaul
baksho.kaul@nihr.ac.uk


Kim Fitzgibbon
kim.fitzgibbon@nihr.ac.uk


Helen Wright
h.wright1@keele.ac.uk


Laurna Bullock
l.bullock@keele.ac.uk


Laurna Bullock
l.bullock@keele.ac.uk


Study Location:

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Be Part of Research - Trial Details - Osteoporosis medicine use for people with dementia - DOMINO study 1.0

Osteoporosis medicine use for people with dementia - DOMINO study 1.0

Recruiting

Open to: Female / Male

Age: 18 Years - N/A

Medical Conditions

Disorders of bone density and structure
Injuries to unspecified part of trunk, limb or body region
Organic, including symptomatic, mental disorders


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


BACKGROUND
Broken bones are sometimes caused by a condition called ‘osteoporosis’. Osteoporosis is where your bones become weaker and are more likely to break easily. People with dementia are more likely to have osteoporosis and broken bones. Broken bones can result in loss of independence, worsening of dementia and need for more support from caregivers. UK guidelines recommend that people with dementia should be prescribed osteoporosis medicines, where appropriate, to prevent broken bones. However, people with dementia are not often offered these medicines, or do not stay on them long enough for them to be effective. First-line osteoporosis tablet medicines have special instructions on how they should be taken, which can be challenging for people with dementia, and they may be more likely to experience side-effects. Alternatively, osteoporosis medicines can be given by injection or infusion once every 6 months or once a year. This can take place in-hospital, or, in some areas, in the patient’s home.

AIMS AND METHODS
Interviews will be completed with people with dementia and relatives/friends of people with dementia. Interviews or focus groups will be completed with health and social care professionals and managers. Interviews and focus groups aim to explore peoples’:
•experiences of deciding about, and receiving different osteoporosis medicines, in different settings (e.g. at home, in hospital).
•barriers and enablers to offering non-tablet osteoporosis medicines, at home or in-hospital, to people with dementia.

OUTPUTS
Interviews and focus groups will inform the development of resources to support people with dementia to be offered and make decisions about osteoporosis medicines that fit best for them and their lives. The potential benefits of these resources are:
•Increased access to more osteoporosis medicine options
•Improved shared decision-making
•More likely to start and continue osteoporosis medicines
•Fewer broken bones with associated disability and deaths

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

05 Mar 2026 01 Jul 2028

Observational

Observational type: Qualitative;



You can take part if:



You may not be able to take part if:


Participants will be excluded if they are : 1) unable to verbally communicate their willingness to take part in the study 2) under 18 years old.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Nottingham University Hospitals NHS Trust - Queen's Medical Centre Campus
    Nottingham University Hospital
    derby Road
    Nottingham
    Nottinghamshire
    NG7 2UH
  • Biddulph Doctors
    Biddulph Primary Care Centre
    wharf Road
    biddulph
    Stoke-on-trent
    Staffordshire
    ST8 6AG
  • Park Medical Centre
    Ball Haye Road
    Leek
    Staffordshire
    ST13 6QR

Laurna Bullock
l.bullock@keele.ac.uk


Gurvinder Gill
gurvinder.gill@nihr.ac.uk


Kim Fitzgibbon
kim.fitzgibbon@nihr.ac.uk


Laurna Bullock
l.bullock@keele.ac.uk


Laurna Bullock
l.bullock@keele.ac.uk


Baksho Kaul
baksho.kaul@nihr.ac.uk


Helen Wright
h.wright1@keele.ac.uk



The study is sponsored by University of Keele and funded by NIHR Academy .




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for Trial ID: CPMS 60546

Last updated 25 March 2026

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