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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Anjali
Shah
+44 (0)1865 613460
anjali.shah@ndorms.ox.ac.uk
Prof
Andrew
Price
+44 (0)1865 223421
andrew.price@ndorms.ox.ac.uk
Dr
Raman
Uberoi
+44 (0)1865 221497
raman.uberoi@ouh.nhs.uk
More information about this study, what is involved and how to take part can be found on the study website.
Knee osteoarthritis
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
This study is looking at whether a new treatment called genicular artery embolisation (GAE) could be a helpful option for people with ongoing pain from knee osteoarthritis. Knee osteoarthritis is a painful condition. In the early stages, patients often benefit from lifestyle changes and exercises. When the knee becomes very damaged, they may require a knee replacement surgery to alleviate the pain and improve symptoms. In between the early and advanced stages, pain can become a major problem. A new treatment has been developed which aims to relieve pain in the knee by blocking (embolisation) small extra blood vessels around the knee. Early studies seem to show some benefit, but a larger study is needed to see if the treatment is effective at reducing pain. If it works, it could help a lot of people with knee osteoarthritis who are in a “treatment gap” between simple care and complex surgery.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
You can take part if:
You may not be able to take part if:
1. Patient previously participated in the GEKO trial (only one knee can be entered into the trial)2. Received a steroid injection in the study knee in the past 6 weeks, or is scheduled to have a steroid injection prior to the study procedure3. Infection or malignancy around the knee4. Inflammatory arthropathy5. History of acute injury to the knee (within 6 months)6. Surgery to the involved knee in the past 6 months7. Previous knee replacement (partial or total) in either limb8. Severe allergic reaction to radiological contrast media, including iodine-based CT-contrast or Gadolinium-based MRI contrast9. Objection (religious or personal) to the use of medical materials made from pigs 10. Allergy to gelatine from pigs (which is within the micro-beads used in the intervention) 11. Known significant renal impairment12. Peripheral artery disease of the affected leg 13. Pregnant or lactating14. Hepatic impairment15. Clotting abnormality16. Osteonecrosis
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Anjali
Shah
+44 (0)1865 613460
anjali.shah@ndorms.ox.ac.uk
Dr
Raman
Uberoi
+44 (0)1865 221497
raman.uberoi@ouh.nhs.uk
Prof
Andrew
Price
+44 (0)1865 223421
andrew.price@ndorms.ox.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by University of Oxford and funded by National Institute for Health and Care Research.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS 68970
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
