Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Novartis Pharmaceuticals 1-888-669-6682
novartis.email@novartis.com


Novartis Pharmaceuticals +41613241111
novartis.email@novartis.com


Study Location:

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Be Part of Research - Trial Details - A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)

A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)

Recruiting

Open to: ALL

Age: 18.0 - 65.0

Medical Conditions

Nephritis
Lupus Nephritis
Lupus Erythematosus, Systemic


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel (administered once following lymphodepletion) versus Standard of Care (SOC) in patients with systemic lupus erythematosus (SLE) with active, refractory lupus nephritis (LN).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Sep 2024 Jun 2029

INTERVENTIONAL

Intervention Type : BIOLOGICAL
Intervention Description : single infusion of rapcabtagene autoleucel

Intervention Arm Group : Regimen 1;

Intervention Type : BIOLOGICAL
Intervention Description : single infusion of rapcabtagene autoleucel

Intervention Arm Group : Regimen 2;

Intervention Type : OTHER
Intervention Description : The treatment regimen must be in line with KDIGO guidelines for treatment of class III/IV LN.

Intervention Arm Group : Standard of Care;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Novartis Investigative Site
    London
    W12 0HS

Novartis Pharmaceuticals +41613241111
novartis.email@novartis.com


Novartis Pharmaceuticals 1-888-669-6682
novartis.email@novartis.com



The study is sponsored by Novartis Pharmaceuticals




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Read full details for Trial ID: NCT06581198
Last updated 10 June 2025

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