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Be Part of Research - Trial Details - A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)

A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)

Not Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Lichen Simplex Chronicus


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This is a parallel, Phase 3, 2-arm study for treatment. The purpose of this study is to measure improvement in pruritus with dupilumab subcutaneous injections compared with placebo injections in male and female participants aged at least 18 years with LSC.

Study details include:

The study duration will be up to 40 weeks. The treatment duration will be up to 24 weeks. The follow-up duration after treatment will be 12 weeks. The number of visits will be 6.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Nov 2024 Jun 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Pharmaceutical form: Solution for injection Route of administration: subcutaneous injection

Intervention Arm Group : Dupilumab;

Intervention Type : DRUG
Intervention Description : Pharmaceutical form: Solution for injection Route of administration: subcutaneous injection

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Investigational Site Number : 8260201
    Southampton
    Hampshire
    SO16 6YD


The study is sponsored by Sanofi and is in collaboration with Regeneron Pharmaceuticals.




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Read full details for Trial ID: NCT06687980
Last updated 19 January 2026

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