Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Tracey Hammett, RN +44 7776498978
t.hammett@ionctura.com


Karen Tonge +44 7776078446
k.tonge@ionctura.com


Study Location:

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Be Part of Research - Trial Details - A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma

A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Melanoma
Uveal Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The goal of this clinical trial is to learn how roginolisib works in comparison to standard treatment in adult patients with uveal/ocular melanoma. The main questions it aims to answer are:

Does roginolisib extend overall survival compared to standard treatment? How does dosing of roginolisib impact quality of life compared to standard treatment?

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Feb 2025 Dec 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : rognolisib

Intervention Arm Group : Arm 1 - Roginolisib 80mg;Arm 3 - Roginolisib 40mg;

Intervention Type : DRUG
Intervention Description : Investigator will choose the most appropriate treatment standardly given to patients

Intervention Arm Group : Arm 2 - Investigator choice of standard of care;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Royal Marsden Hospital
    London
    SW3 6JJ
  • East and North Hertfordshire NHS Trust (Mount Vernon Cancer Centre)
    Northwood
    Middlesex
    HA6 2RN
  • The Clatterbridge Cancer Centre NHS Foundation Trust
    Bebington
    Wirral
    CH63 4JH
  • Beatson West of Scotland Cancer Centre, Glasgow (NHS Greater Glasgow & Clyde)
    Glasgow
    G12 0YN
  • University College London Hospital NHS
    London
    NW1 2PG
  • University Hospital Southampton NHS Foundation
    Southampton
    SO16 6YD


The study is sponsored by iOnctura




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Read full details for Trial ID: NCT06717126
Last updated 28 April 2025

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