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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Other diseases of blood and blood-forming organsMalignant neoplasm of breast
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Patients with advanced cancers are often treated with chemotherapy which can reduce the effectiveness of the body's own immune system and leave patients exposed to infection. The manufacturers of chemotherapy drugs generally suggest using the same amount of drug for everybody, however, we know that because everyone is different, people end up with more or less of the drug circulating in their blood even after they have been given the same dose.
A software program (a "Dosing Tool") has been developed by Physiomics (research partner) to provide information to doctors on how certain chemotherapies will affect individual patients. The program may help doctors to make smarter decisions about exactly how much drug to give to different people and also how and when to use other expensive drugs that counteract the effect of chemotherapy on the immune system.
In order to make the Dosing Tool work, doctors need to collect additional information through additional blood tests on how individuals respond to their chemotherapy. We will develop this dosing Tool by running a clinical trial where women with breast cancer will be monitored for the depletion of a type of white blood cells called neutropenia. For this trial run at Blackpool Victoria hospital, a nurse will travel to patient's home where needed to collect small volumes (a few microliters) of blood. As it can be inconvenient or even impossible for some patients to return to their cancer care centre to have these tests, Physiomics is working with another company, Beyond Blood, which is developing a system to enable patients to obtain blood test results from small samples.
We believe a combination of the Dosing Tool and Beyond Blood at-home test may eventually be approved for use to help ensure patients get the best outcomes when they are being treated for breast cancer.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Type: Management of Care;Active Monitoring;
You can take part if:
You may not be able to take part if:
Exclusion criteria: o Patients with autoimmune disease receiving active treatments o Participant is unable to give informed consent
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by BLACKPOOL TEACHING HOSPITALS NHS FOUNDATION TRUST and funded by Innovate UK .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 62995
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