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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

BeiGene 1.877.828.5568
clinicaltrials@beigene.com


Study Location:

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Be Part of Research - Trial Details - A Study of BGB-11417 in Participants With Myeloid Malignancies

A Study of BGB-11417 in Participants With Myeloid Malignancies

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Myelodysplastic Syndromes
Myeloproliferative Disorders
Myelodysplastic-Myeloproliferative Diseases


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The study will determine the safety, tolerability, recommended Phase 2 dose (RP2D) and preliminary efficacy of BGB-11417 as monotherapy and in combination with azacitidine in participants with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)or MDS/myeloproliferative neoplasm (MPN) .

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

May 2021 Feb 2028

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Oral administration for 10, 21, 14 or 28 days on a 28-day cycle.

Intervention Arm Group : Part 3: AML and MDS Cohorts;Parts 1 and 2: AML Cohorts;

Intervention Type : DRUG
Intervention Description : Intravenous or subcutaneous administration for 7 days.

Intervention Arm Group : Part 3: AML and MDS Cohorts;Parts 1 and 2: AML Cohorts;Parts 1 and 2: MDS Cohorts;

Intervention Type : DRUG
Intervention Description : Oral administration for 8 days on second cycle only.

Intervention Arm Group : Part 3: AML and MDS Cohorts;

Intervention Type : DRUG
Intervention Description : Oral administration for 28 days on a 28-day cycle.

Intervention Arm Group : Part 3: AML and MDS Cohort;

Intervention Type : DRUG
Intervention Description : Oral administration for 10, 14 or 21 days on a 28-day

Intervention Arm Group : Parts 1 and 2: MDS Cohorts;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Edinburgh Cancer Centre
    Edinburgh
    EH4 2XU
  • The Christie Hospital
    Greater Manchester
    M20 4BX


The study is sponsored by BeiGene




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Read full details for Trial ID: NCT04771130
Last updated 07 May 2025

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