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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Anna
Freeman
a.freeman@soton.ac.uk
Dr
Anna
Freeman
a.freeman@soton.ac.uk
Nikki
Cullum
Nikki.cullum@uhs.nhs.uk
Chronic lower respiratory diseases
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The burden of poor asthma control remains high. Many patients with asthma remain symptomatic despite optimised treatment including targeted biologic therapies. Well-controlled asthma is heavily reliant on ongoing medical treatment, with potential for medication side effects. However, it is increasingly recognised that problematic asthma is a multidimensional state comprising numerous treatable traits that merit targeted approaches. Ideally these approaches should facilitate self-management approaches that support patients’ behaviour change, optimise their psychological wellbeing and deliver a goal of patient empowerment. Collectively addressing pulmonary, extrapulmonary and behavioural/ psychological treatable traits in such an integrated way has potential to significantly impact the burden of asthma at an individual patient level. We hypothesis that a multimodal intervention comprising a structured responsive exercise training programme (SRETP) and psychological/behavioural support through healthy conversations (HC), breathing retraining and dietary support for patients with difficult asthma
i. is safe and acceptable in this patient group.
ii. will increase exercise capacity and quality of life.
iii. may help identify potential biological mechanisms that mediate impact of multimodal lifestyle interventions. We are co-developing with patients a 24 week intervention to be delivered in the community comprising prescribed exercise, breathing retraining, dietary support and behaviour change support. We will assess patients at baseline, 6 and 12 months in person, with blood and urine sampling and lung function testing, and virtually and 3 and 9 months to assess response and whether it results in sustained behaviour change.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Interventional type: Education or Self-Management;Psychological & Behavioural;Complex Intervention;Physical;
You can take part if:
You may not be able to take part if:
Investigator determined significant change in regular asthma medication during trial period Other medical or psychiatric conditions limiting ability to exercise or that may in the opinion of the study clinician carry inherent risk for exercise Contraindication to ISWT Positive pregnancy test in females of childbearing age Beta blocker treatment
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Anna
Freeman
a.freeman@soton.ac.uk
Nikki
Cullum
Nikki.cullum@uhs.nhs.uk
Dr
Anna
Freeman
a.freeman@soton.ac.uk
The study is sponsored by UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST and funded by BMA CHARITIES TRUST FUND .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 63276
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
