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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Lauren
Baker
L.baker5@herts.ac.uk
Dr
Lindsay
Bottoms
l.bottoms@herts.ac.uk
Dr
Lindsay
Bottoms
l.bottoms@herts.ac.uk
Johanne
Brooks
johanne.brooks@nhs.net
Johanne
Brooks
johanne.brooks@nhs.net
Noninfective enteritis and colitis
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Crohn's disease (CD) is a long‐term inflammatory condition of the digestive system. People with CD often have unpredictable and debilitating symptoms, including abdominal pain, diarrhoea, and fatigue. They also require long-term treatment with frequent negative effects and often need surgery and hospitalisations. Therefore, people with CD report a low health-related quality of life.
Exercise might be a simple, safe, low-cost intervention for improving HRQOL in people with CD. This is because it can potentially simultaneously improve several aspects of physical, mental and social well-being. Adults with CD have been shown to be less active than the general population. One barrier to exercise is lack of time, however whole-body vibration exercise (where you stand and squat on a vibrating plate) can be done over a much shorter duration and at a lower intensity to gain potentially similar or at times greater benefits.
This study begins to understand whether undertaking a supervised 6-week vibration exercise programme for adults with mild to moderately active Crohn’s disease improves HRQoL and other symptoms such as fatigue.
The study will recruit 168 adults with mild to moderately active CD. After initial assessments, participants will be randomised to a 6-week supervised whole body vibration exercise programme alongside a lifestyle education programme or lifestyle education programme only. Both groups will receive the same contact time with the research team and their usual care for their CD. Participants will complete assessments of their HRQOL, disease activity, inflammation, physical fitness, subjective fatigue, muscle fatigue and mental health. We will also conduct a phone interview at the end of the trial to understand the participants' experience of receiving the vibration exercise.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Interventional type: Education or Self-Management;Complementary Therapy;Physical;
You can take part if:
You may not be able to take part if:
Exclusion Criteria • Severe or uncontrolled medical conditions that make it undesirable for the patient to participate • Coexistent serious autoimmune disease such as rheumatoid arthritis or systemic sclerosis • Planned major surgery within the first 3 months after randomization • Are pregnant, or are planning pregnancy within the first 3 months after randomization • Poor tolerability to venepuncture or lack of adequate venous access for required blood sampling • Participation in another clinical trial for which concurrent participation is deemed inappropriate • Any orthopedic implants (hip, knee, spine)
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Lindsay
Bottoms
l.bottoms@herts.ac.uk
Lauren
Baker
L.baker5@herts.ac.uk
Dr
Lindsay
Bottoms
l.bottoms@herts.ac.uk
Johanne
Brooks
johanne.brooks@nhs.net
Johanne
Brooks
johanne.brooks@nhs.net
The study is sponsored by University of Hertfordshire and funded by CROHN'S & COLITIS FOUNDATION OF AMERICA, INC. .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 61345
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
