Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Anthony Kong 44+2078486004
Anthony.Kong@kcl.ac.uk


Ifigenia Vasiliadou 44+2078486004
Ifigenia.1.Vasiliadou@kcl.ac.uk


Study Location:

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Be Part of Research - Trial Details - Thermotherapy in Addition to SOC Palliative Radiotherapy

Thermotherapy in Addition to SOC Palliative Radiotherapy

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Squamous Cell Carcinoma of Head and Neck


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study aims to investigate the efficacy and safety profile of superficial hyperthermia (wIRA) in addition to standard of care (SOC) palliative radiotherapy in patients with inoperable/incurable locally advanced or recurrent/metastatic HNSCC or cutaneous SCC superficial tumours not suitable for radical treatment.

The investigators will assess the best objective response rate (ORR) of patients with Inoperable/incurable or recurrent/metastatic HNSCC or cSCC with superficial lesion(s) treated with the combination of superficial hyperthermia (wIRA) and palliative radiotherapy.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Oct 2024 Oct 2027

INTERVENTIONAL

Intervention Type : DEVICE
Intervention Description : Superficial hypothermia will be delivered using a CE-marked water-filtered infrared A (wIRA) machine (hydrosun® TWH1500)

Intervention Arm Group : Cutaneous squamous cell carcinoma;Head and neck squamous cell carcinoma;Locally recurrent breast cancer;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Guy's and St. Thomas NHS Foundation Trust
    London
    SE1 9RT
  • Guy's Cancer Centre
    London


The study is sponsored by King's College London and is in collaboration with Guy's and St Thomas' NHS Foundation Trust.




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Read full details for Trial ID: NCT06659146
Last updated 26 August 2025

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