Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Miss Nicole Keyworth
+44 2381205154
cvlp@soton.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - NHS Cancer Vaccine Launch Pad (NHS CVLP)

NHS Cancer Vaccine Launch Pad (NHS CVLP)

Medical Conditions

Cancer vaccine studies in various cancer types


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


Personalised cancer vaccines are a type of cancer treatment designed to target an individual’s unique cancer cells. They are created by analysing a patient’s tumour and identifying specific DNA changes that are unique to that cancer, then using that information to create a vaccine tailored to that patient. The intention is that the cancer vaccine will stimulate the immune system to specifically recognise and destroy the cancer cells.
The NHS Cancer Vaccine Launch Pad (CVLP) is looking to find people who may be able to take part in research trials for personalised vaccines to treat cancer. By supporting these trials, the CVLP aims to speed up the development of personalised treatments for cancer patients.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

31 Aug 2024 01 May 2025

Upon consent, the following will occur:
1. Small sections of the tumor will be cut from the diagnostic block by a histopathologist (a doctor who specializes in studying tissues). These sections will be sent to CVLP partners for nucleic acid extraction and sequencing. Nucleic acids are molecules like DNA and RNA that carry genetic information.
2. A blood sample, up to 30 milliliters, will be drawn and sent to CVLP partners. This sample may be tested for germline nucleic acid (genetic information you were born with) and tumor circulating free DNA (genetic material released by the tumor into the bloodstream).
3. Baseline demographic (like age and gender) and clinical data will be recorded by the clinical or research team and sent with the biological material in a pseudonymised form (using codes instead of names to protect your identity). This data will also be centrally held by Southampton Clinical Trials Unit (SCTU) to coordinate with cancer vaccine trial partners and sites. A clinical liaison team will oversee this process.
4. During Phase 1, sequencing data will be held by industry partners. If you are eligible for a cancer vaccine trial, the clinical liaison team will inform your clinical team and local trial sites. Pseudonymised codes will be used to identify patients when communicating with clinical teams or linking patients with NHS cancer vaccine trial sites. Any other information shared outside the NHS CVLP framework will also be pseudonymised.
5. If you are eligible for a cancer vaccine trial, your home clinical or research team, or the team at the nearest cancer vaccine trial site, will approach you for further discussion and a separate consent.


NHS cancer patients in England aged over 16 years with capacity to consent.

You can take part if:



You may not be able to take part if:


1. Under the age of 16 years2. Incapable of giving informed consent


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Churchill Hospital
    Churchill Hospital Old Road Headington
    Oxford
    OX3 7LE
  • Southmead Hospital
    Southmead Road Westbury-on-trym
    Bristol
    BS10 5NB
  • Royal Blackburn Hospital
    Haslingden Road
    Blackburn
    BB2 3HH
  • Royal Surrey County Hospital
    Egerton Road
    Guildford
    GU2 7XX
  • Royal Sussex County Hospital
    Eastern Road
    Brighton
    BN2 5BE
  • Weston Park Hospital
    Whitham Road
    Sheffield
    S10 2SJ
  • Queen Elizabeth Hospital
    Woolwich Stadium Road Woolwich
    London
    SE18 4QH
  • Royal Stoke University Hospital
    Newcastle Road
    Stoke-on-trent
    ST4 6QG
  • Nottingham City Hospital
    Hucknall Road
    Nottingham
    NG5 1PB
  • St. James's University Hospital
    Beckett Street
    Leeds
    LS9 7TF
  • Queens Hospital
    Rom Valley Way
    Romford
    RM7 0AG
  • Walsall Manor Hospital
    Moat Road
    Walsall
    WS2 9PS
  • Yeovil District Hospital
    Higher Kingston
    Yeovil
    BA21 4AT
  • Addenbrookes
    Addenbrookes Hospital Hills Road
    Cambridge
    CB2 0QQ
  • Derriford Hospital
    Derriford Road Derriford
    Plymouth
    PL6 8DH
  • Leeds General Infirmary
    Great George Street
    Leeds
    LS1 3EX
  • The James Cook University Hospital
    Marton Road
    Middlesbrough
    TS4 3BW
  • North Devon District Hospital
    Raleigh Park
    Barnstaple
    EX31 4JB
  • Rochdale Infirmary
    Whitehall Street
    Rochdale
    OL12 0NB
  • Sunderland Royal Hospital
    Kayll Road
    Sunderland
    SR4 7TP
  • University Hospital Lewisham
    Lewisham High Street
    London
    SE13 6LH
  • Salford Royal Hospital
    Stott Lane Eccles
    Salford
    M6 8HD
  • Cheltenham General Hospital
    Sandford Road
    Cheltenham
    GL53 7AN
  • Stoke Mandeville Hospital
    Mandeville Road
    Aylesbury
    HP21 8AL
  • Musgrove Park Hospital
    Parkfield Drive
    Taunton
    TA1 5DA
  • Royal Devon and Exeter Hospital
    Royal Devon & Exeter Hospital Barrack Road
    Exeter
    EX2 5DW
  • Warwick Hospital
    Lakin Road
    Warwick
    CV34 5BW
  • Royal United Hospital Bath
    Combe Park
    Bath
    BA1 3NG
  • Ipswich Hospital
    Heath Road
    Ipswich
    IP4 5PD
  • Southampton
    Southampton General Hospital Tremona Road
    Southampton
    SO16 6YD
  • Cumberland Infirmary
    Newtown Road
    Carlisle
    CA2 7HY
  • Fairfield General Hospital
    Fairfield General Hospital Rochdale Old Road
    Bury
    BL9 7TD
  • The Royal Oldham Hospital
    Rochdale Road
    Oldham
    OL1 2JH
  • Gloucestershire Royal Hospital
    Great Western Road
    Gloucester
    GL1 3NN
  • Bristol Haematology & Oncology Centre
    Horfield Road
    Bristol
    BS2 8ED
  • Hillingdon Hospital
    Hillingdon Hospital Pield Heath Road
    Uxbridge
    UB8 3NN
  • Royal Lancaster Infirmary
    Ashton Road
    Lancaster
    LA1 4RP
  • Wycombe Hospital
    Queen Alexandra Road
    High Wycombe
    HP11 2TT
  • Eastbourne District General Hospital
    Kings Drive
    Eastbourne
    BN21 2UD
  • Tunbridge Wells Hospital
    The Tunbridge Wells Hospital Tonbridge Road Pembury
    Tunbridge Wells
    TN2 4QJ
  • West Cumberland Hospital
    Homewood Hensingham
    Whitehaven
    CA28 8JG
  • North Tyneside General Hospital
    Rake lane
    North Shields
    NE29 8NH
  • Colchester General Hospital
    Colchester District General Hosp. Charter Way Turner Road
    Colchester
    CO4 5JL
  • Conquest Hospital
    The Ridge
    St. Leonards-on-sea
    TN37 7RD
  • Queens Medical Centre, Nottingham University Hospital
    Derby Road
    Nottingham
    NG7 2UH
  • New Cross Hospital Royal Wolverhampton
    Wolverhampton Road Heath Town
    Wolverhampton
    WV10 0QP
  • Maidstone
    Maidstone Hospital Hermitage Lane
    Maidstone
    ME16 9QQ
  • South Tyneside District General Hospital
    Harton Lane
    South Shields
    NE34 0PL

This information has not yet been provided by the study team. You'll have an opportunity to discuss any risks and benefits that may be associated with this study prior to consenting to taking part.

Miss Nicole Keyworth
+44 2381205154
cvlp@soton.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by NHS England and funded by NHS England as sponsor will be receiving funding from multiple industry companies.




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Read full details for Trial ID: ISRCTN13053675

Or CPMS 57835

Last updated 09 October 2024

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.