Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Prof Sally Singh
sally.singh@nhs.net


Ms Gwen Barwell
performlctu@leicester.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

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Be Part of Research - Trial Details - Personalised exercise rehabilitation for people with multiple long-term conditions: Main Trial
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Personalised exercise rehabilitation for people with multiple long-term conditions: Main Trial

Recruiting

Open to: All Genders

Age: Mixed

Sheffield Leicester Newcastle upon Tyne Brighton Bodmin York Hartlepool London Lincoln Glasgow Wakefield Dartford Worcester Liverpool Newcastle upon Tyne Luton Preston Daventry Walsall Bournemouth Cardiff

Medical Conditions

Multiple long-term conditions

This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

14 Feb 2025 30 Apr 2027

All participants will be asked to attend an initial (baseline) research visit and a 3-month and 12-month follow-up visit.
These visits will take place at their local hospital or rehabilitation clinic and take about 2-3 hours to complete. They will include physical assessment measures such walking tests and handgrip strength. In the randomised controlled trial participants will be randomly allocated to either take part in the PERFORM exercise rehabilitation programme or continue with their usual care. Participants in the prospective cohort study will receive the PERFORM exercise rehabilitation instead of standard cardiac or pulmonary rehabilitation.
After participants have been randomised, if they are in a social media site they will be given the link to access a PERFORM Facebook group.
Participants who receive the exercise rehabilitation programme will also have the opportunity to take part in an interview that includes their thoughts on the programme, the barriers or facilitators whilst taking part and suggestions for improvement.
Participants who take part in the social media group will also have the opportunity to take part in an interview that includes their thoughts on the Facebook group, the pros and cons of using social media and suggestions for improvement.


Patients aged 18 years and over who have two or more long-term conditions that are identified as having a potential benefit to an exercise rehabilitation programme. The trial is looking for participants who are not currently eligible for standard cardiac or pulmonary rehabilitation to go into the randomised controlled trial, and for participants who ARE eligible for standard cardiac or pulmonary rehabilitation to go into the prospective cohort study.

You can take part if:



You may not be able to take part if:


1. Unable to give consent for the study2. Unable to communicate in English (carer or support worker may be available)3. Known contraindications to exercise (as defined by the American College of Sports Medicine) ("ACSM’s guidelines for exercise testing and prescription 11th Ed. 2021.") to include3.1. Unstable cardiac disease3.2. Current fever3.3. Significant aortic aneurysm (more than 5.5 cm)4. Unable to attend in-person training sessions5. Participation in an exercise rehabilitation programme in the last 6 months6. Unstable psychiatric disorder that limits or disrupts group-based interventions7. On an End of Life pathway with a prognosis of less than 12 months survival8. Active malignancy (on chemotherapy/radiotherapy/planned urgent surgery)9. For people on a surgical waiting list a pragmatic decision will be made on a case-by-case basis of the type of surgery, urgency and likely wait times10. Pregnancy11. Under 18’s12. Living in a Nursing Home.13. Unsafe to exercise in a group without 1:1 supervision (e.g. significant risk of falls, significant psychiatric issues) 14. Greater than 80% predicted on the ISWT at initial assessment


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Sheffield Teaching Hospitals NHS Foundation Trust
    Northern General Hospital Herries Road
    Sheffield
    S5 7AU
  • University Hospitals of Leicester NHS Trust
    Leicester Royal Infirmary Infirmary Square
    Leicester
    LE1 5WW
  • The Newcastle upon Tyne Hospitals NHS Foundation Trust
    Freeman Hospital Freeman Road High Heaton
    Newcastle upon Tyne
    NE7 7DN
  • Sussex Community NHS Foundation Trust
    Brighton General Hospital Elm Grove
    Brighton
    BN2 3EW
  • Cornwall Partnership NHS Foundation Trust
    Carew House Beacon Technology Park Dunmere Road
    Bodmin
    PL31 2QN
  • York and Scarborough Teaching Hospitals NHS Foundation Trust
    York Hospital Wigginton Road
    York
    YO31 8HE
  • North Tees and Hartlepool NHS Foundation Trust
    University Hospital of Hartlepool Holdforth Road
    Hartlepool
    TS24 9AH
  • Central London Community Healthcare NHS Trust
    Ground Floor 15 Marylebone Road
    London
    NW1 5JD
  • Lincolnshire Community Health Services NHS Trust
    Beech House Witham Park Waterside South
    Lincoln
    LN5 7JH
  • University of Glasgow
    University Avenue
    Glasgow
    G12 8QQ
  • Mid Yorkshire Teaching NHS Trust
    Pinderfields Hospital Aberford Road
    Wakefield
    WF1 4DG
  • Dartford and Gravesham NHS Trust
    Darent Valley Hospital Darenth Wood Road
    Dartford
    DA2 8DA
  • Herefordshire and Worcestershire Health and Care NHS Trust
    Unit 2 Kings Court Charles Hastings Way
    Worcester
    WR5 1JR
  • Liverpool John Moores University
    Rodney House 70 Mount Pleasant
    Liverpool
    L3 5UX
  • Healthworks Newcastle
    Health Resource Centre Adelaide Terrace
    Newcastle upon Tyne
    NE4 8BE
  • University of Bedfordshire
    University Square
    Luton
    LU1 3JU
  • Heartbeat (Preston)
    Sir Tom Finney Way
    Preston
    PR1 6PA
  • Reach for Health
    Stefen Hill, Stefen Hill Ground, Western Ave,
    Daventry
    NN11 4UD
  • Heart Care Wallsall
    12 Portland St,
    Walsall
    WS2 8AB
  • Health Sciences University
    13-15 Parkwood Road
    Bournemouth
    BH5 2DF
  • Cardiff Metropolitan University
    Po Box 377 Llandaff
    Cardiff
    CF5 2SG

The PERFORM rehabilitation programme is aimed to help people manage their multiple long-term health conditions and participants may experience some benefit in taking part, but this
intervention is being tested therefore benefits are not guaranteed. The information collected
may help in caring for other patients in the future.
There are minor disadvantages of taking part; these include travel to and from the research
centre and the time taken to complete the above-listed assessments.
The researchers don’t expect patients to be harmed in any way by taking part in our study, but they could experience some discomfort when completing the walking assessments. Also, if the participant is chosen to take part in the PERFORM rehabilitation programme this will involve exercise and there is a risk that they might initially have muscle soreness.

Prof Sally Singh
sally.singh@nhs.net


Ms Gwen Barwell
performlctu@leicester.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by University of Leicester and funded by National Institute for Health and Care Research.



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Read full details for Trial ID: ISRCTN59323331

Or CPMS: 62643

Last updated 25 September 2026

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