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Contact Information:

Verena Hinze
verena.hinze@psych.ox.ac.uk


Verena Hinze
verena.hinze@psych.ox.ac.uk


Study Location:

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Be Part of Research - Trial Details - Distress in adolescents with chronic pain: Who is at risk, when, & why

Distress in adolescents with chronic pain: Who is at risk, when, & why

Recruiting

Open to: All Genders

Age: 12 Years - 19 Years

Medical Conditions

Intentional self-harm
General symptoms and signs


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Background: Chronic pain is a serious concern in young people; up to 38% are affected by chronic pain. For many, chronic pain can last into adulthood, causing disability and distress, including feelings of hopelessness and entrapment. At its worst, pain may co-occur with suicidal and self-harm thoughts and behaviours. Previously, we have shown that nearly one in 10 adolescents in the UK reported persistent/recurrent pain and self-harm thoughts or behaviours. But not everyone with chronic pain will develop such severe distress. Therefore, it is crucial that we better understand who is at risk, when, and why.
Aims: In this study, we address the following research question: What are the factors that determine why some young people with chronic pain may experience suicidal distress but not others, and through which mechanisms does chronic pain increase such distress over time? This is important so we can help those who need it at the right time.
Methods: 70 adolescents with chronic pain (12-19 years) will be invited to take part in this study. They will complete three detailed surveys and brief questions on their experience of pain, suicidal distress, and relevant mechanisms 5 times per day for 30 days, using a method called ‘Ecological Momentary Assessment’. This method is similar to a digital diary and will enable us to explore how feelings of pain and suicidal distress might change (increase or decrease) over short periods (hours/days/weeks) of time in the daily lives of adolescents with chronic pain. We also aim to identify psychological and social factors that might predict those changes (who is at risk, and through which psychosocial processes such suicidal distress emerges over time).
Impact: As chronic pain brings young people in contact with healthcare services, our findings can directly inform clinical care. Understanding the factors that might explain who is at risk is vital to identify vulnerable youth, and knowing when and through which processes risk increases is key to identify effective support and help healthcare professionals in offering prompt and effective care to adolescents with chronic pain.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

27 Sep 2024 01 Mar 2026

Observational

Observational type: Cohort study;



You can take part if:



You may not be able to take part if:


Exclusion Criteria The participant may not enter the study if ANY of the following apply: • If some serious acute pathology (e.g.,infection,fracture,disease process (e.g.,cancer with a potentially fatal trajectory)) or surgical procedure is the cause of the resulting pain complaint. • If the patient is too psychologically unstable to safely participate in this research,based on clinical judgment (e.g.,experiences of acute psychosis)


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Royal United Hospital
    Combe Park
    Bath
    Avon
    BA1 3NG
  • Nuffield Orthopaedic Centre
    Windmill Road
    headington
    Oxford
    Oxfordshire
    OX3 7HE


The study is sponsored by University of Oxford and funded by MEDICAL RESEARCH FOUNDATION .




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for Trial ID: CPMS 64178

Last updated 21 July 2025

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