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Contact Information:

Epsilogen Clinical Trials +44 (0) 203 657 7612
info@epsilogen.com


Study Location:

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Be Part of Research - Trial Details - A Study of MOv18 IgE in Folate Receptor Alpha-expressing Platinum Resistant Ovarian Cancer

A Study of MOv18 IgE in Folate Receptor Alpha-expressing Platinum Resistant Ovarian Cancer

Recruiting

Open to: FEMALE

Age: 18.0 - N/A

Medical Conditions

Ovarian Neoplasms
Carcinoma, Ovarian Epithelial


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


EPS101-10-02 is a Phase Ib open label, multicentre clinical trial comprising of a Dose Escalation phase (Part 1) followed by a Dose Expansion phase (Part 2) of MOv18 IgE in patients with folate receptor alpha-expressing (5% or higher) platinum resistant ovarian cancer

The dose escalation part of the study will primarily assess the safety and tolerability of MOv18 IgE in ascending dose cohorts, until the determination of the maximum tolerated dose (MTD) or maximum administered dose (MAD).

Part 2 (dose expansion) will further assess the safety, tolerability and anti-tumour activity of MOv18 IgE.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Sep 2024 Jul 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : MOv18 IgE is an anti-FRα monoclonal antibody (mAb) of the IgE class

Intervention Arm Group : Part 1 and Part 2;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • University College London Hospital
    London
    NW1 2BU
  • Edinburgh Cancer Research Centre
    Edinburgh
    EH4 2XR
  • Leeds Teaching Hospitals NHS Trust
    Leeds
    LS9 7LP
  • Cambridge University - Addenbrooke's Hospital
    London
    CB2 0QQ
  • Guy's Hospital
    London
    SE1 3SS
  • University Hospital Southampton NHS Foundation Trust
    Southampton
    SO16 6HU
  • Bristol Haematology and Oncology Centre
    Bristol
    BS2 8ED

Epsilogen Clinical Trials +44 (0) 203 657 7612
info@epsilogen.com



The study is sponsored by Epsilogen Ltd




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Read full details for Trial ID: NCT06547840
Last updated 17 December 2024

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