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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Seagen Pfizer CT.gov Call Center 1-800-718-1021
ClinicalTrials.gov_Inquiries@pfizer.com


Study Location:

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Be Part of Research - Trial Details - A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors

A Study of PF-08046052/SGN-EGFRd2 in Advanced Solid Tumors

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Carcinoma
Colorectal Neoplasms
Carcinoma, Non-Small-Cell Lung
Squamous Cell Carcinoma of Head and Neck


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study will test the safety of a drug called PF-08046052/SGN-EGFRd2 in participants with advanced solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease.

Participants will have cancer that cannot be removed (unresectable) or has spread through the body (metastatic).

This study will have three parts. Parts A and B of the study will find out how much PF-08046052/SGN-EGFRd2 should be given to participants. Part C will use the dose found in parts A and B to find out how safe PF-08046052/SGN-EGFRd2 is and if it works to treat solid tumor cancers.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Nov 2023 Jan 2029

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Given into the vein (IV; intravenously)

Intervention Arm Group : PF-08046052/SGN-EGFRd2;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • University College London Hospital, NIHR UCLH Clinical Research Facility
    London
    W1T 7HA
  • The Christie NHS Foundation Trust
    Manchester
    M20 4BX

Seagen Pfizer CT.gov Call Center 1-800-718-1021
ClinicalTrials.gov_Inquiries@pfizer.com



The study is sponsored by Seagen, a wholly owned subsidiary of Pfizer




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Read full details for Trial ID: NCT05983133
Last updated 07 July 2025

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