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Be Part of Research - Trial Details - A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004).

A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004).

Not Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Carcinoma
Carcinoma, Renal Cell


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The primary objective of the study is to compare V940 plus pembrolizumab to placebo plus pembrolizumab in participants with renal cell carcinoma (RCC) with respect to disease-free survival (DFS) as assessed by the investigator. The primary hypothesis is that V940 plus pembrolizumab is superior to placebo plus pembrolizumab with respect to DFS.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Apr 2024 Jan 2028

INTERVENTIONAL

Intervention Type : BIOLOGICAL
Intervention Description : IM injection

Intervention Arm Group : V940 + Pembrolizumab;

Intervention Type : BIOLOGICAL
Intervention Description : IV infusion

Intervention Arm Group : Placebo + Pembrolizumab;V940 + Pembrolizumab;

Intervention Type : BIOLOGICAL
Intervention Description : IM injection

Intervention Arm Group : Placebo + Pembrolizumab;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • St Bartholomew's Hospital ( Site 1000)
    London
    London, City Of
    EC1A 7BE
  • Addenbrooke's Hospital ( Site 1004)
    Cambridge
    Cambridgeshire
    CB2 2QQ
  • The Christie NHS Foundation Trust ( Site 1001)
    Manchester
    m20 4bx
  • Gartnavel General Hospital-Clinical Trials Unit ( Site 1002)
    Glasgow
    Glasgow City
    G12 0YN
  • Western General Hospital ( Site 1003)
    Edinburgh
    Midlothian
    EH4 2XU


The study is sponsored by Merck Sharp & Dohme LLC and is in collaboration with ModernaTX, Inc..




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Read full details for Trial ID: NCT06307431
Last updated 19 March 2025

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