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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Amgen Call Center 866-572-6436
medinfo@amgen.com


Study Location:

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Be Part of Research - Trial Details - Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors

Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors

Recruiting

Open to: ALL

Age: 18.0 - 100.0

Medical Conditions

Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The primary objective of this study is to:

* Evaluate the safety and tolerability of AMG 305 in adult participants * Determine the optimal biologically active dose (OBD), at or below the maximum tolerated dose (MTD) with MTD 1 as the maximum tolerated starting dose and MTD 2 as the maximum tolerated target dose * Determine the recommended phase 2 dose (RP2D)

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2023 Jun 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Short-term intravenous (IV) infusion

Intervention Arm Group : Part A: Dose Exploration;Part B: Dose Expansion;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Freeman Hospital
    Newcastle
    NE7 7DN
  • Christie Hospital
    Manchester
    M20 4BX
  • Royal Marsden Hospital
    Sutton
    SM2 5PT
  • Sarah Cannon Research Institute UK
    London
    W1G 6AD
  • Beatson West of Scotland Cancer Centre
    Glasgow
    G12 0YN

Amgen Call Center 866-572-6436
medinfo@amgen.com



The study is sponsored by Amgen




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Read full details for Trial ID: NCT05800964
Last updated 07 May 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.