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Be Part of Research - Trial Details - A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

Not Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Neoplasm Metastasis
Neoplasms, Squamous Cell
Carcinoma, Squamous Cell
Head and Neck Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The main aim of this study is to check for side effects and tolerability of TAK-186 (also known as MVC-101) in adults with unremovable advanced or metastatic cancer. Another aim is to characterize and evaluate the activity of TAK-186 (MVC-101).

Participants may receive treatment throughout the study for a maximum of 13 months and will be followed up at 30 days and 90 days and then every 12 weeks for up to 48 weeks after the last treatment.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Mar 2021 Sep 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : TAK-186 IV infusion.

Intervention Arm Group : Cohort Expansion Phase: NSCLC;Dose Escalation Phase;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • The Christie - PPDS
    Manchester
    M20 4BX
  • Sarah Cannon Research Institute UK - SCRI - PPDS
    London
    Middlesex
    W1G 6AD


The study is sponsored by Takeda




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Read full details for Trial ID: NCT04844073
Last updated 12 March 2025

This page is to help you find out about a research study and if you may be able to take part

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