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Contact Information:

Adam Glass +442890976378
a.glass@qub.ac.uk


Jon Silversides j.silversides@qub.ac.uk


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Be Part of Research - Trial Details - CMR Right Ventricular Contractile Reserve Following Lung Resection
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CMR Right Ventricular Contractile Reserve Following Lung Resection

Recruiting

Open to: ALL

Age: 18.0 - N/A

Belfast

Medical Conditions

This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Feasibility study investigating CMR dobutamine stress testing before and after lung resection

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jul 2023 Dec 2024

OBSERVATIONAL

Intervention Type : DIAGNOSTIC_TEST
Intervention Description : Dobutamine stress testing will be undertaken in keeping with local departmental clinical guidelines with a graded increase in dobutamine infusion up to a maximum of 10microgram/kg/min. The patients' medications will be managed in keeping with the usual clinical practice and departmental guidelines.

At rest and on each graded level of dobutamine infusion we will collect cine loops of the cardiac cycle including a short-axis stack of the ventricles, a four-chamber view and flow imaging perpendicular to the main, left and right pulmonary arteries.

Post-processing will be dual reported by blinded observers using the Argus analysis software (Siemens) according to a standardised protocol. A safety report of each CMR scan will be generated by a consultant cardiologist, any abnormalities identified will be referred to the appropriate medical speciality and highlighted to the patient's clinical team.

Intervention Arm Group : Lung resection;

Intervention Type : DIAGNOSTIC_TEST
Intervention Description : blood samples will be collected pre-operatively, in recovery, on post-operative days 1 and 2, and at 4-8 weeks post-operatively

Intervention Arm Group : Gastrectomy;Lung resection;Oesophagectomy;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Belfast Health and Social Care Trust
    Belfast
    Northern Ireland
    BT12 6BA

Jon Silversides j.silversides@qub.ac.uk


Adam Glass +442890976378
a.glass@qub.ac.uk



The study is sponsored by Belfast Health and Social Care Trust



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Read full details for Trial ID: NCT06465277
Last updated 02 October 2024

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