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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

AstraZeneca Clinical Study Information Center 1-877-240-9479
information.center@astrazeneca.com


Study Location:

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Be Part of Research - Trial Details - A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

Recruiting

Open to: ALL

Age: 18.0 - 70.0

Medical Conditions

Lupus Erythematosus, Systemic
Lupus Erythematosus, Cutaneous


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study aims to evaluate the efficacy and safety of subcutaneous (SC) anifrolumab versus placebo in adult participants with cutaneous lupus erythematosus (CLE).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2024 Dec 2027

INTERVENTIONAL

Intervention Type : COMBINATION_PRODUCT
Intervention Description : Anifrolumab will be provided as a solution for injection in accessorized pre-filled syringe (aPFS).

Intervention Arm Group : Stage 1: Anifrolumab;

Intervention Type : OTHER
Intervention Description : Matching placebo solution for injection in aPFS.

Intervention Arm Group : Stage 1: Placebo;

Intervention Type : COMBINATION_PRODUCT
Intervention Description : Anifrolumab will be provided as a solution for injection in accessorized pre-filled syringe (aPFS).

Intervention Arm Group : Stage 2: Anifrolumab;

Intervention Type : OTHER
Intervention Description : Matching placebo solution for injection in aPFS.

Intervention Arm Group : Stage 2: Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Research Site
    Cambridge
    CB2 0QQ
  • Research Site
    London
    NW1 2PG
  • Research Site
    London
    NW3 2QG
  • Research Site
    London
    SE1 7EH
  • Research Site
    London
    SE5 9RS
  • Research Site
    Leeds
    LS2 9JT
  • Research Site
    Newcastle upon Tyne
    NE1 4LP

AstraZeneca Clinical Study Information Center 1-877-240-9479
information.center@astrazeneca.com



The study is sponsored by AstraZeneca and is in collaboration with Parexel.




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Read full details for Trial ID: NCT06015737
Last updated 25 March 2025

This page is to help you find out about a research study and if you may be able to take part

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