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Be Part of Research - Trial Details - Use of PET-MR in Head and Neck Cancer Patients - Diagnostic and Therapeutic Applications

Use of PET-MR in Head and Neck Cancer Patients - Diagnostic and Therapeutic Applications

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Head and Neck Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The primary research question to be answered in this project is "Are patients with locally-advanced head and neck cancer able to tolerate a PET-MRI scan when they are immobilised in a radiotherapy treatment shell?" This will be assessed by measuring the proportion of patients that complete the full scanning protocol and by obtaining participant feedback on their experience of completing the scan.

The secondary question is "Can a PET-MRI scan fused with a planning CT scan improve the accuracy in radiotherapy planning of patients with head and neck cancer? Accuracy will be assessed by:

1. Comparing the radiotherapy target volumes and radiotherapy plans with and without the use of a PET-MRI scan. 2. Comparing inter- and intra-observer variability in treatment contours with and without the use of a PET-MRI scan within and between oncologists and implications of that.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jan 2024 Oct 2024

INTERVENTIONAL

Intervention Type : DIAGNOSTIC_TEST
Intervention Description : Patients that participate in the current study will have an extra PET-MRI scan, which will expose them to a small amount (4 - 6 mSv) of extra radiation.

Intervention Arm Group : PET-MRI within 1 week of planning scan.;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Cancer Research Centre at Weston Park Hospital
    Sheffield
    England
    S1O 2SJ


The study is sponsored by Sheffield Teaching Hospitals NHS Foundation Trust




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Read full details for Trial ID: NCT06032663
Last updated 22 April 2024

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