Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Boehringer Ingelheim 1-800-243-0127
clintriage.rdg@boehringer-ingelheim.com


Study Location:

Skip to Main Content
English | Cymraeg
Be Part of Research - Trial Details - DAREON™-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapy

DAREON™-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapy

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Small Cell Lung Carcinoma


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study is open to adults with extensive stage small cell lung cancer. The study is in people with advanced cancer that had previously received platinum-based chemotherapy and are eligible to receive a single agent chemotherapy treatment.

The purpose of this study is to find the highest dose of BI 764532 that people can tolerate when taken together with a single agent chemotherapy. BI 764532 is an antibody-like molecule that may help the immune system fight cancer.

Participants may continue to take BI 764532 as long as they benefit from treatment and can tolerate it. During this time, participants visit the study site regularly. The visits also depend on the response to the treatment. At the study visits, the doctors check the health of the participants, take necessary laboratory tests, and note any health problems that could have been caused by the study treatment.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Feb 2024 Jun 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : BI 764532

Intervention Arm Group : Part A: BI 764532 high dose + topotecan/single agent chemotherapy;Part A: BI 764532 low dose + topotecan/single agent chemotherapy;Part A: BI 764532 medium dose + topotecan/single agent chemotherapy;Part B: BI 764532 + topotecan;

Intervention Type : DRUG
Intervention Description : Topotecan

Intervention Arm Group : Part A: BI 764532 high dose + topotecan/single agent chemotherapy;Part A: BI 764532 low dose + topotecan/single agent chemotherapy;Part A: BI 764532 medium dose + topotecan/single agent chemotherapy;Part B: BI 764532 + topotecan;

Intervention Type : DRUG
Intervention Description : single agent chemotherapy

Intervention Arm Group : Part A: BI 764532 high dose + topotecan/single agent chemotherapy;Part A: BI 764532 low dose + topotecan/single agent chemotherapy;Part A: BI 764532 medium dose + topotecan/single agent chemotherapy;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Leicester Royal Infirmary
    Leicester
    LE1 5WW


The study is sponsored by Boehringer Ingelheim




We'd like your feedback

Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.


Is this study information helpful?

What will you do next?

Read full details for Trial ID: NCT05990738
Last updated 10 June 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.