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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Pregnancy-associated osteoporosis
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Pregnancy-associated osteoporosis (PAO) is a rare condition that typically presents with multiple vertebral fractures during pregnancy or lactation. The cause of PAO is poorly understood. It is known that bone is normally lost from the maternal skeleton during pregnancy and lactation to meet the needs of the growing foetus and infant during breastfeeding, but the degree of bone loss is modest and very rarely results in clinically apparent osteoporosis. It has been speculated that individuals who develop PAO may have pre-existing osteoporosis which worsens during pregnancy as the result of physiological bone loss or may experience exaggerated bone loss for reasons that are unclear. The aim of this study is to document the characteristics of women who have been diagnosed with PAO, its clinical features and the mode of disease presentation. A specific aim will be to explore the possible role of genetic factors by gathering information on family history of osteoporosis and PAO and conducting genetic profiling. A control group will also volunteer to give a blood sample for genetic profiling. The longer-term objective of the study is to gain a greater understanding of why PAO occurs in the hope that this will improve clinical outcomes in patients with this rare but serious condition.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
You can take part if:
You may not be able to take part if:
Does not meet the inclusion criteria
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Miss
Kathryn
Berg
+44 (0)1316518726
kathryn.berg@ed.ac.uk
The study is sponsored by Accord (United Kingdom) and funded by Royal Osteoporosis Society.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS 52578
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
