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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Prof
Dan
Cuthbertson
Dan.Cuthbertson@liverpool.ac.uk
Theresa
Hydes
theresa.hydes@liverpool.ac.uk
Prof
Dan
Cuthbertson
Dan.Cuthbertson@liverpool.ac.uk
Prof
Dan
Cuthbertson
Dan.Cuthbertson@liverpool.ac.uk
Theresa
Hydes
theresa.hydes@liverpool.ac.uk
Diseases of liverDiabetes mellitusObesity and other hyperalimentation
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Background: Metabolic associated steatotic liver disease (MASLD) occurs where there is too much fat in the liver due to obesity or diabetes. MASLD causes liver scarring and increases your risk of heart and kidney disease. We have set up the ‘Knowsley Healthy Liver Clinic’ in-line with the latest clinical guidelines. Patients aged 18-70 years with diabetes or obesity will be invited to attend this community clinic to screen them for MASLD (using a bedside test,Fibroscan) and associated conditions (diabetes,obesity,high blood pressure,high cholesterol,heart disease,kidney disease). Patients will receive education (feedback on results,lifestyle advice) and offered referral to community weight management services. The clinical team will optimise patients’ medication and refer people with advanced disease to a specialist.
Aim: Examine the effectiveness and cost-effectiveness of the Knowsley Healthy Liver Clinic.
Research plan:
1. Collect data on patients’ health (metabolic,liver,kidneys,heart) from baseline and 6-month follow-up appointments to see if there is any improvement after people attend the baseline liver clinic.
2. Examine the costs associated with the clinic and whether the liver clinic leads to improvement in quality-of-life scores assessed using a questionnaire to see if the service provides good value for money
3. Examine if the clinic is associated with high levels of patient satisfaction using a questionnaire
4. Examine the longer-term health outcomes for people attending the clinic for up to 5 years
To demonstrate weight loss of ≥3% we need to see 436 patients. We aim to see 480 patients allowing for a 10% non-attendance rate.
This research will involve collecting and analysing clinical data for patients attending the clinic and asking patients to complete questionnaires on their quality-of-life and satisfaction with the service. The only assessment performed for research purposes rather than clinical need is the 6-month follow-up Fibroscan examination.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Type: Other;
You can take part if:
You may not be able to take part if:
People will not be invited to attend the Knowsley Healthy Liver Clinic if they meet any of the following criteria: • People under 18 years old,or over 70 years old • People with cirrhosis or who have undergone a liver transplant • People with a life limiting illness or those receiving end of life care
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Prof
Dan
Cuthbertson
Dan.Cuthbertson@liverpool.ac.uk
Theresa
Hydes
theresa.hydes@liverpool.ac.uk
Prof
Dan
Cuthbertson
Dan.Cuthbertson@liverpool.ac.uk
Theresa
Hydes
theresa.hydes@liverpool.ac.uk
Prof
Dan
Cuthbertson
Dan.Cuthbertson@liverpool.ac.uk
The study is sponsored by University of Liverpool and funded by GUTS UK CHARITY .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 60973
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
