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Be Part of Research - Trial Details - A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants with Early Alzheimer's Disease (ALTITUDE-AD)

A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants with Early Alzheimer's Disease (ALTITUDE-AD)

Not Recruiting

Open to: ALL

Age: 50.0 - 90.0

Medical Conditions

Alzheimer Disease


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The primary purpose of this study is to evaluate the efficacy of sabirnetug infusions administered once every four weeks (Q4W) in slowing cognitive and functional decline as compared to placebo in participants with early Alzheimer's disease.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Feb 2024 Oct 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Intravenous sabirnetug

Intervention Arm Group : DBT Period: sabirnetug 50 mg/kg;Double-blind Treatment (DBT) Period: sabirnetug 35 mg/kg;Open-Label Extension (OLE) Period: sabirnetug 35 mg/kg;

Intervention Type : DRUG
Intervention Description : Intravenous Placebo

Intervention Arm Group : DBT Period: Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Re:Cognition Health - London
    London
    Greater London
  • St. Pancras Clinical Research Ltd.
    London
    Greater London
  • Panthera Bio-Partners - Rochdale
    Rochdale
    Greater Manchester
  • Re:Cognition Health - Winchester
    Winchester
    Hampshire
  • Neuroclin Glasgow
    Motherwell
    Lanarkshire
  • Panthera Bio-Partners - Preston
    Preston
    Lancashire
  • Re:Cognition Health - Guildford
    Guildford
    Surrey
  • Panthera Biopartners - Sheffield
    Sheffield
    Yorkshire
  • Re:Cognition Health - Bristol
    Bristol


The study is sponsored by Acumen Pharmaceuticals




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Read full details for Trial ID: NCT06335173
Last updated 17 December 2024

This page is to help you find out about a research study and if you may be able to take part

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