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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

AstraZeneca Clinical Study Information Center 1-877-240-9479
information.center@astrazeneca.com


Study Location:

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Be Part of Research - Trial Details - Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Medical Conditions

Heart Failure


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This is a Phase III, international, multi-centre, randomised, double-blind, parallel-group, double-dummy, active-controlled, event-driven study in patients with chronic HF and impaired kidney function who had a recent HF event. The aim is to evaluate the effect of balcinrenone/dapagliflozin vs dapagliflozin, given once daily on top of other classes of SoC, on CV death and HF events.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Apr 2024 Jun 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : 1 capsule of balcinrenone/dapagliflozin 15 mg/10 mg and 1 tablet of matching placebo for dapagliflozin 10 mg once daily, oral use

Intervention Arm Group : balcinrenone/dapagliflozin 15 mg/10 mg;

Intervention Type : DRUG
Intervention Description : 1 capsule of balcinrenone/dapagliflozin 40 mg/10 mg and 1 tablet of matching placebo for dapagliflozin 10 mg once daily, oral use

Intervention Arm Group : balcinrenone/dapagliflozin 40 mg/10 mg;

Intervention Type : DRUG
Intervention Description : 1 tablet of dapagliflozin 10 mg and 1 capsule of matching placebo for balcinrenone/dapagliflozin once daily, oral use

Intervention Arm Group : dapagliflozin 10 mg;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Research Site
    London
    EC1M 6BQ
  • Research Site
    Sheffield
    S5 7AU
  • Research Site
    London
    SE5 9RS
  • Research Site
    Airdrie
    ML6 0JS
  • Research Site
    Exeter
    EX2 5DW
  • Research Site
    High Wycombe
    HP11 2TT
  • Research Site
    Middlesborough
    TS4 3BW
  • Research Site
    Wakefield
    WF1 4DG
  • Research Site
    Portsmouth
    PO6 3LY
  • Research Site
    Cambridge
    CB2 0AY
  • Research Site
    Clydebank
    G81 4DY
  • Research Site
    Barnet
    EN5 3DJ
  • Research Site
    Sunderland
    SR4 7TP
  • Research Site
    Harefield
    UB9 6JH
  • Research Site
    Lincoln
    LN2 5QY
  • Research Site
    Kent
    BR6 8ND
  • Research Site
    Hastings
    TN37 7RD
  • Research Site
    King's Lynn
    PE30 4ET

AstraZeneca Clinical Study Information Center 1-877-240-9479
information.center@astrazeneca.com



The study is sponsored by AstraZeneca




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Read full details for Trial ID: NCT06307652
Last updated 03 April 2025

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