Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Sasha Gayle
sasha.gayle@icr.ac.uk


Prof Johann de Bono
johann.de-bono@icr.ac.uk


Study Location:

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Be Part of Research - Trial Details - MICROBIOME MOLECULAR CHARACTERISATION (MMC)

MICROBIOME MOLECULAR CHARACTERISATION (MMC)

Recruiting

Open to: Female / Male

Age: 18 Years - 90 Years

Medical Conditions

Malignant neoplasms of male genital organs


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study aims to answer the question as to whether the composition of gut microorganisms/microbiata (also known as 'gut flora'),found in the intestines,plays a role in how the body responds to anti-cancer treatments,specifically anti-cancer treatments for Prostate Cancer. This trial will assess exactly what types of microorganisms are present in the gut of males undergoing diagnostic investigations for confirmation of prostate cancer (i.e. patients at the very start of their treatment). Those patients who go on to have treatment (e.g. hormonal therapies,chemotherapies and novel agents such as immunotherapies),will be followed-up to know how they responded to their treatment. We will look for possible links between the composition of the microbiata within the gut of these patients and the response to their treatment.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

23 Oct 2023 30 Mar 2028

Observational

Observational type: Clinical Laboratory Study;



You can take part if:



You may not be able to take part if:


1. The presence of any haematological disorders,including coagulation disorders,which would be a contraindication if patient were to undergo a biopsy. 2. The presence of bleeding disorders or any other haematological alterations that would preclude the patient from safely undergoing a biopsy 3. Any psychiatric illness/social situations that would limit compliance with study requirements. 4. Presence of any concurrent condition or situation,which,in the investigator’s opinion,may put the patient at significant risk,may confound the study results,or may interfere significantly with the patient’s participation in the study.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • The Royal Marsden Hospital (surrey)
    Downs Road
    Sutton
    Surrey
    SM2 5PT
  • The Royal Marsden Hospital (london)
    Fulham Road
    London
    Greater London
    SW3 6JJ
  • St Helier Hospital
    Wrythe Lane
    Carshalton
    Surrey
    SM5 1AA

Sasha Gayle
sasha.gayle@icr.ac.uk


Prof Johann de Bono
johann.de-bono@icr.ac.uk



The study is sponsored by Institute of Cancer Research: Royal Cancer Hospital and funded by Medical Research Council (MRC) .





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for Trial ID: CPMS 60981

Last updated 03 April 2025

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