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Be Part of Research - Trial Details - A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

Medical Conditions

Alzheimer Disease
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Tauopathies
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The reason for this study is to assess the safety and efficacy of donanemab in participants with early Alzheimer's disease. The study duration including screening and follow-up is up to 93 weeks.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Oct 2022 May 2028

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Administered IV

Intervention Arm Group : Donanemab;

Intervention Type : DRUG
Intervention Description : Administered IV

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Charing Cross Hospital
    London
    W6 8RF
  • Royal Preston Hospital
    Preston
    PR2 9HT
  • St. George's Hospital
    London
    SW17 0RE
  • Re:Cognition Health - Birmingham
    Birmingham
    B16 8LT
  • Moorgreen Hospital
    Southampton
    SO30 3JB
  • Re:Cognition Health - Plymouth
    Plymouth
    PL6 8BT
  • The Rice Centre - Royal United Hospital
    Bath
    BA1 3NG
  • Dementia Research Unit
    Crowborough
    TN6 1NY
  • Re:Cognition Health - Bristol
    Bristol
    BS32 4SY
  • Surrey and Borders Partnership NHS Foundation Trust
    Chertsey
    KT16 9AU
  • Re:Cognition Health - Guildford
    Guildford
    GU2 7YD
  • University College London Hospital
    London
    W1CN 3BG
  • Re:Cognition Health - London
    London
    W1G 8TB
  • Queen's Medical Centre, Nottingham University Hospitals
    Nottinghamshire
    NG7 2UH
  • Re:Cognition Health - Winchester
    Winchester
    SO23 8SR


The study is sponsored by Eli Lilly and Company




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Read full details for Trial ID: NCT05508789
Last updated 08 May 2026

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.