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Contact Information:

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com 855-907-3286
Clinical.Trials@bms.com


First line of the email MUST contain NCT # and Site #.


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Be Part of Research - Trial Details - Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease
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Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease

Recruiting

Open to: ALL

Age: 50.0 - 80.0

Winchester Enfield London Guildford Bristol Southampton Southampton Birmingham Bristol Bath London Chertsey

Medical Conditions

Alzheimer Disease

This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to assess the effectiveness, safety, and tolerability of BMS-986446 an Anti-MTBR Tau Monoclonal Antibody in participants with Early Alzheimer's Disease.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Mar 2024 Apr 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Specified dose on specified days

Intervention Arm Group : BMS-986446 Dose A;BMS-986446 Dose B;

Intervention Type : OTHER
Intervention Description : Specified dose on specified days

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Local Institution - 0103
    Winchester
    HAM
    SO21 1HU
  • Local Institution - 0121
    Enfield
    LND
    EN3 4GS
  • Local Institution - 0100
    London
    LND
    W1G 9JF
  • Local Institution - 0090
    Guildford
    SRY
    GU2 7YD
  • Local Institution - 0127
    Bristol
    BS10 5NB
  • Local Institution - 0237
    Southampton
    Hampshire
    SO16 6YD
  • Local Institution - 0230
    Southampton
    HAM
    SO30 3JB
  • Local Institution - 0244
    Birmingham
    BIR
    B16 8LT
  • Local Institution - 0245
    Bristol
    BST
    BS32 4SY
  • Local Institution - 0247
    Bath
    SOM
    BA1 3NG
  • St Pancras Clinical Research (SPCR)
    London
    LND
    EC2Y 8EA
  • Surrey and Borders NHS Foundation Trust Headquarters
    Chertsey
    Surrey
    KT16 9AU

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com 855-907-3286
Clinical.Trials@bms.com


First line of the email MUST contain NCT # and Site #.



The study is sponsored by Bristol-Myers Squibb



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Read full details for Trial ID: NCT06268886
Last updated 01 July 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.   

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