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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Mrs
Karen
Willoughby
+44 (0)1223 217580
kw369@medschl.cam.ac.uk
Dr
Kenneth
Poole
More information about this study, what is involved and how to take part can be found on the study website.
Osteoporosis
This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.
Osteoporosis is a condition that weakens bones, making them fragile and more likely to break. It is a condition that develops slowly over several years and is often only diagnosed when a minor fall or sudden impact causes a bone break (or fracture). Osteoporosis particularly affects the spine and hips, resulting in breaks of the bone in these areas. Whilst treatment of osteoporosis is now quite straightforward, detection is difficult. In the UK, osteoporosis causes 200,000 fractures of the spine yearly in women and men. The pain of a small spine fracture can feel like ordinary backache, and as a result patients are often left undiagnosed, so many small fractures are common. This eventually leads to poorer mobility and increased pain for the sufferer. The aim of this study is to find out whether it is possible to identify osteoporosis earlier, leading to improved treatment and better outcomes. To do this the researchers will be looking at special scans called CT scans (computerised tomography) that patients are already having for various reasons, and using some new software that has been developed to make more accurate diagnosis of osteoporosis and bone fractures. A CT scan uses x-rays and a computer to create images of the inside of the body; two million are performed each year in the UK, often for abdominal or pelvic problems. In this study, CT images are reviewed using a new software to identify osteoporosis enabling early treatment and potentially preventing future fractures. This new technology makes it simple to measure a patient’s bone density quickly and identify vertebral fractures from CT images of a patient's torso or pelvis. Bone density measurements of the spine and hips are performed on images acquired from any CT scanner. This study is a feasibility study to see if it is realistic to develop into a national trial, so the researchers will be looking at how well they can recruit participants to the study, and as they hope to follow up with a questionnaire after one year, they will also be looking at how many people stay in the study, or drop out.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
2022 Protocol article in https://pubmed.ncbi.nlm.nih.gov/35613783/ (added 27/05/2022)
You can take part if:
You may not be able to take part if:
1. Aged > 902. Bilateral metalwork in hips3. Unable to provide valid consent4. Known to be receiving prescription treatment for osteoporosis other than calcium/vitamin D (i.e. bisphosphonate drug, strontium ranelate, denosumab, raloxifene or teriparatide)5. Prone CT scan
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Kenneth
Poole
Mrs
Karen
Willoughby
+44 (0)1223 217580
kw369@medschl.cam.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by Cambridge University NHS Foundation Trust and funded by National Institute for Health Research.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS: 41112
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
