Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Miss Millie Beament
+44 (0)20 3448 4773
m.beament@ucl.ac.uk


Prof Nicholas Fox
+44 (0)20 3448 4773
n.fox@ucl.ac.uk


Study Location:

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Be Part of Research - Trial Details - Biomarkers and rapid imaging in dementia diagnosis

Biomarkers and rapid imaging in dementia diagnosis

Recruiting

Open to: All Genders

Age: Adult

Medical Conditions

Dementia


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


MRI is an essential part of the diagnostic workup in dementia, however, the time taken and cost limit its availability. Reduction in scan time will solve these issues. This study aims to develop an ultra-fast MRI scan cutting the gold-standard MRI scan from 30 to 7 minutes, with these scans providing non-inferior images to aid in dementia diagnosis.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

21 Mar 2022 01 Jul 2025

The study involves a standard clinical MRI scan (30 minutes) with an additional 7 minutes for the ultra-fast scan, donation of a blood sample and 10 minutes of neuropsychology


Patients referred to the National Hospital for Neurology and Neurosurgery

You can take part if:



You may not be able to take part if:


1. Unable to tolerate a routine MRI scan plus a 7-minute fast-MRI scan2. Unable to tolerate draw blood by venepuncture


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • National Hospital for Neurology & Neurosurgery
    Queen Square
    London
    WC1N 3BG

There is no direct benefit for participating in the study. Some people experience minor discomfort, bruising or swelling following a blood draw. There is also a small risk of developing an infection at the site of blood draw. MRI scans may feel slightly uncomfortable due to the noise the machine makes. The table you lie on may feel hard, and the room may be cool, but the medical team will do everything they can to make you comfortable and blankets may be provided. You may be tired or sore from lying
in one position for a long time. Some people experience claustrophobia when having a scan, but the medical team will do whatever they can to help you relax before and during the scan. The MRI scanner produces loud tapping, knocking, chirping and squeaking sounds during the scans. Before your scan, the technicians will give you disposable foam ear plugs and headphones to wear to protect your hearing from the loud noise. Cognitive testing can be mentally tiring but is unlikely to cause any harm.


The study is sponsored by University of London and funded by Biogen; Alzheimer's Society; Rosetrees Trust.




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What will you do next?

Read full details for Trial ID: ISRCTN12777415

Or CPMS 51048

Last updated 19 July 2024

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.