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Contact Information:

ABBVIE CALL CENTER 844-663-3742
abbvieclinicaltrials@abbvie.com


Study Location:

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Be Part of Research - Trial Details - Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA)

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA)

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Fallopian Tube Neoplasms
Peritoneal Neoplasms
Hypersensitivity


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRα) expression.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Dec 2022 Mar 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Participants will receive MIRV 6.0 mg/kg adjusted ideal body weight (AIBW) plus Bevacizumab 15mg/kg every 3 weeks

Intervention Arm Group : Arm 1;

Intervention Type : DRUG
Intervention Description : Participants will receive Bevacizumab 15mg/kg every 3 weeks

Intervention Arm Group : Arm 2;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Cheltenham General Hospital
    Cheltenham
    GL53 7AN
  • Singleton Hospital
    Swansea
    Wales
    SA2 8PP
  • Guy's and St Thomas' NHS Foundation Trust
    London
    SE1 9TR
  • Southampton University NHS Trust
    Southampton
    SO16 6YD
  • The Royal Marsden Hospital - Chelsea
    Fulham
    London
    SW3 6JJ
  • The Royal Marsden Hospital - Sutton
    Sutton
    Surrey
    SM2 5PT
  • The Christie / The Christie NHS Foundation Trust
    Manchester
    M20 4BX
  • Mount Vernon Cancer Centre East and North Hertfordshire NHS Trust Site
    Northwood
    HA6 2RN


The study is sponsored by AbbVie and is in collaboration with GOG Foundation.




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Read full details for Trial ID: NCT05445778
Last updated 18 March 2025

This page is to help you find out about a research study and if you may be able to take part

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