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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

AstraZeneca Clinical Study Information Center 1-877-240-9479
information.center@astrazeneca.com


Study Location:

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Be Part of Research - Trial Details - AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Adenocarcinoma
Stomach Neoplasms
Biliary Tract Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of this study is to assess the safety, tolerability, efficacy, pharmacokinetics (PK), and immunogenicity of AZD0901 as monotherapy and in combination with anti-cancer agents in participants with locally advanced unresectable or metastatic solid tumours expressing CLDN18.2.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Dec 2023 Dec 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Antibody-drug conjugate/Biologic

Intervention Arm Group : Sub Study 1 - AZD0901 MONOTHERAPY;Sub Study 2 - AZD0901 IN COMBINATION WITH ANTI-CANCER AGENTS IN PANCREATIC DUCTAL ADENOCARCINOMA;Sub Study 3: AZD0901 MONOTHERAPY IN BILIARY TRACT CANCER;

Intervention Type : DRUG
Intervention Description : Chemotherapy agents

Intervention Arm Group : Sub Study 2 - AZD0901 IN COMBINATION WITH ANTI-CANCER AGENTS IN PANCREATIC DUCTAL ADENOCARCINOMA;

Intervention Type : DRUG
Intervention Description : Chemotherapy agents

Intervention Arm Group : Sub Study 2 - AZD0901 IN COMBINATION WITH ANTI-CANCER AGENTS IN PANCREATIC DUCTAL ADENOCARCINOMA;

Intervention Type : DRUG
Intervention Description : Chemotherapy agents

Intervention Arm Group : Sub Study 2 - AZD0901 IN COMBINATION WITH ANTI-CANCER AGENTS IN PANCREATIC DUCTAL ADENOCARCINOMA;

Intervention Type : DRUG
Intervention Description : Chemotherapy agents

Intervention Arm Group : Sub Study 2 - AZD0901 IN COMBINATION WITH ANTI-CANCER AGENTS IN PANCREATIC DUCTAL ADENOCARCINOMA;

Intervention Type : DRUG
Intervention Description : Chemotherapy agents

Intervention Arm Group : Sub Study 2 - AZD0901 IN COMBINATION WITH ANTI-CANCER AGENTS IN PANCREATIC DUCTAL ADENOCARCINOMA;

Intervention Type : DRUG
Intervention Description : Chemotherapy agents

Intervention Arm Group : Sub Study 2 - AZD0901 IN COMBINATION WITH ANTI-CANCER AGENTS IN PANCREATIC DUCTAL ADENOCARCINOMA;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Research Site
    Oxford
    OX3 7LE
  • Research Site
    London
    NW3 2QG
  • Research Site
    Glasgow
    G12 0YN
  • Research Site
    Leeds
    LS9 7TF

AstraZeneca Clinical Study Information Center 1-877-240-9479
information.center@astrazeneca.com



The study is sponsored by AstraZeneca




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Read full details for Trial ID: NCT06219941
Last updated 03 July 2025

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