We'd like your feedback
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Sondos
Albadri
sondos@liverpool.ac.uk
Teslimat
Ajeigbe
tajeigbe@liverpool.ac.uk
Diseases of oral cavity, salivary glands and jaws
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Previous research has told us that children with medical issues,or from deprived backgrounds,suffer from worse oral health and increased amounts of dental decay. There has,however,been little research into whether changes to teeth on the molecular level could partly be responsible for why children in these groups often experience worse oral health. Proteins are a type of large molecule; if we can establish what proteins are inside the teeth of healthy children,we will then have the opportunity to compare how tooth proteins may change in disease and deprivation with further research in the future. Greater understanding about any potential differences will provide more opportunities to create specific preventive and/or treatment strategies to help ensure good oral health for all children.
It appears that children’s baby teeth have not yet been researched in this way. This project will use scientific techniques (mass spectrometry and bioinformatics) at the University of Liverpool to determine the proteins present in children's baby teeth,as well as their functions. This project will rely on the donation of sound teeth that have naturally fallen out of the mouths of healthy children (aged approximately 5-8 years old),as well as teeth donated following their removal as part of dental treatment under general anaesthetic in Liverpool. The project aims to be complete within a year and has been funded by a joint grant from the Royal College of England's Faculty of Dental Surgery and the British Society of Paediatric Dentistry.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Clinical Laboratory Study;
You can take part if:
You may not be able to take part if:
1-Teeth from children diagnosed with a medical condition,behavioural condition (e.g. autism,ADHD),syndrome or congenital abnormality (e.g. cleft lip and/or palate) 2-Carious teeth,severely worn teeth,or teeth with any other pathology 3-Non-central incisor teeth 4-Teeth that have exfoliated or been removed for more than 2 weeks before storage at -80oC 5-Teeth returned without written consent or a Participant Information form
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by University of Liverpool and funded by Royal College of Surgeons of England .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 60653
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
